Department of Family Medicine, Gangnam Severance Hospital, Yonsei University College of Medicine, 211 Eonju-ro, Gangnam-gu, Seoul 06273, Korea.
Department of Medicine, Graduate School of Medicine, Yonsei University, 50-1 Yonsei-ro, Seodaemun-gu, Seoul 03722, Korea.
Int J Environ Res Public Health. 2022 Apr 29;19(9):5433. doi: 10.3390/ijerph19095433.
We compared the improvement in components of metabolic syndrome (MS) before and after lifestyle modification, as determined by daily step counts (on a wrist-worn Fitbit®) in participants with and without MS recruited from volunteers attending medical health checkup programs. A linear mixed model was used to analyze the change in MS components between participants with and without MS by group × time interaction. Multiple logistic regression analysis after adjustment for confounders was used to obtain odds ratios (ORs) and 95% confidence intervals (CIs) for improvements in MS components per 1000-steps/day increments. Waist circumference, triglycerides, fasting plasma glucose, and diastolic blood pressure were significantly different between participants with and without MS (group × time: p = 0.010, p < 0.001, p = 0.025, and p = 0.010, respectively). Multivariable-adjusted ORs (95% CI) of improvement in MS components per 1000-steps/day increments were 1.24 (1.01−1.53) in participants with and 1.14 (0.93−1.40) in participants without MS. Walking improved MS components more in individuals with than without MS. From a public health perspective, walking should be encouraged for high-risk MS individuals.
我们比较了通过佩戴在手腕上的 Fitbit®记录的日常步数（参与者自报），来评估生活方式改变对患有和不患有代谢综合征（MS）的参与者的 MS 各组分的改善情况。采用线性混合模型，通过组×时间的交互作用，分析 MS 各组分在患有和不患有 MS 的参与者之间的变化。采用多变量逻辑回归分析，对混杂因素进行调整后，计算 MS 各组分每增加 1000 步/天的改善的比值比（OR）和 95%置信区间（CI）。患有和不患有 MS 的参与者之间腰围、甘油三酯、空腹血糖和舒张压存在显著差异（组×时间：p = 0.010，p < 0.001，p = 0.025，p = 0.010）。多变量调整后的 OR（95%CI），MS 各组分每增加 1000 步/天的改善幅度在患有 MS 的参与者中为 1.24（1.01-1.53），在不患有 MS 的参与者中为 1.14（0.93-1.40）。与不患有 MS 的参与者相比，MS 患者的步行对 MS 各组分的改善效果更为显著。从公共卫生的角度来看，应鼓励高危 MS 人群多走路。
