Richter Diana, Clever Katharina, Mehnert-Theuerkauf Anja, Schönfelder Antje
Department of Medical Psychology and Medical Sociology, University Medical Center Leipzig, 04103 Leipzig, Germany.
Department of Psychosomatics and Psychotherapy, MEDIAN Centre for Rehabilitation Schmannewitz, 04774 Dahlen, Germany.
Cancers (Basel). 2022 Apr 22;14(9):2092. doi: 10.3390/cancers14092092.
Due to the high survival rates of many young cancer patients and a high risk of second tumors, fear of cancer recurrence (FCR) can cause serious impairment for adolescent and young adult (AYA) cancer patients. The aim of this study is to analyze the structure of the Fear of Disease Progression Questionnaire (FoP-Q-12) to better understand the construct of FCR. We performed a cross-sectional survey on a sample of AYA patients aged 15-39 years with different tumor entities. FCR was measured using the FoP-Q-12, and a network analysis was conducted to examine the relationship of FCR symptoms. The importance of individual items in the network was determined using centrality analyses. A total of 247 AYA patients (81.8% female, median age 31.0 years) participated in the study. The mean FCR score in the sample was 35.9 (SD = 9.9). The majority of patients reported having high FCR (59.5%), according to the established cut-off. The two questionnaire items with the strongest association related to fears about work, and the most central symptom was the fear of serious medical interventions. The centrality of emotional issues in the sample indicates that these symptoms should be prioritized in the development of interventions targeting FCR. Further research should address this topic with larger samples of patients in other age groups and in longitudinal studies.
由于许多年轻癌症患者的高生存率以及二次肿瘤的高风险，对癌症复发的恐惧（FCR）会对青少年和青年（AYA）癌症患者造成严重损害。本研究的目的是分析疾病进展恐惧问卷（FoP-Q-12）的结构，以更好地理解FCR的构成。我们对15至39岁患有不同肿瘤类型的AYA患者样本进行了横断面调查。使用FoP-Q-12测量FCR，并进行网络分析以检查FCR症状之间的关系。使用中心性分析确定网络中各个项目的重要性。共有247名AYA患者（81.8%为女性，中位年龄31.0岁）参与了研究。样本中的平均FCR得分为35.9（标准差=9.9）。根据既定的临界值，大多数患者报告有较高的FCR（59.5%）。与对工作的恐惧关联最强的两个问卷项目，最核心的症状是对严重医疗干预的恐惧。样本中情感问题的中心性表明，在针对FCR的干预措施制定中应优先考虑这些症状。进一步的研究应以其他年龄组的更大患者样本和纵向研究来探讨这个话题。
