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同伴互助对青年癌症幸存者自我效能的影响(Peer2Me):一项综合队列设计的研究结果

Peer2Me - impact of peer support on self-efficacy in young adult cancer survivors (YA-CS): findings from a comprehensive cohort design.

作者信息

Brock Hannah, Dwinger Sarah, Friedrich Michael, Sender Annekathrin, Geue Kristina, Mehnert-Theuerkauf Anja, Bergelt Corinna, Richter Diana

机构信息

Department of Medical Psychology and Medical Sociology, Comprehensive Cancer Center Central Germany (CCCG), University Medical Center Leipzig, Philipp-Rosenthal-Str. 55, 04103, Leipzig, Germany.

Department of Medical Psychology, University Medical Center Hamburg-Eppendorf, Hamburg, Germany.

出版信息

BMC Cancer. 2025 May 26;25(1):943. doi: 10.1186/s12885-025-14323-5.

Abstract

BACKGROUND

Numerous studies suggest that young adult cancer survivors (YA-CS) experience unmet needs regarding informational exchange about their disease and emotional support from peers. Currently, there is a lack of evaluated peer support interventions in Germany. This study aimed to evaluate the effectiveness of "Peer2Me", a three-month one-to-one peer mentoring program, designed to improve self-efficacy among YA-CS.

METHODS

This study conducted a bi-center comprehensive cohort design and enrolled YA-CS (18-39 years old) undergoing acute treatment in Leipzig and Hamburg (Germany) across all tumour entities diagnosed within the last six months. YA-CS were allocated by preference to the intervention (IG, receiving peer mentoring) and comparison group (CG, care as usual). Following mentor training, tandems were matched by diagnosis, age, and gender. YA-CS completed questionnaires at baseline (t1), post-intervention (3 months later, t2) and three months post-intervention (t3). The primary outcome was self-efficacy measured with the Generalized Self-Efficacy Scale (GSES) and the Cancer Behaviour Inventory (CBI-B). Statistical analyses included mixed-design ANOVA and ANCOVA, controlling for baseline scores.

RESULTS

Out of 274 eligible YA-CS, a total of 106 YA-CS (IG: n = 77, CG: n = 29) completed the study. Two-thirds of YA-CS (66.7%) expressed a clear preference to be allocated to the IG. Baseline differences in coping behaviors were noted, with the IG demonstrating lower scores, suggesting a higher need for support. The ANCOVA revealed no group effects for the change of mean GSES scores from t1 to t2 (p =.897) or from t1 to t3 (p =.779). Also, no significant differences in the improvement of mean CBI-B scores between groups could be found from t1 to t2 (p =.903) or from t1 to t3 (p =.995).

CONCLUSIONS

The "Peer2Me" program did not demonstrate a significant effect on improving self-efficacy among YA-CS during acute treatment. Although interest in peer mentoring was high, the intervention showed no measurable benefit in comparison with standard care. While the need for support was evident, further research is required to optimize peer interventions for this group.

TRIAL REGISTRATION

The study was retrospectively registered on February 4, 2022 at clinicaltrials.gov (NCT05336318).

摘要

背景

众多研究表明,年轻成年癌症幸存者(YA-CS)在疾病信息交流和同伴情感支持方面存在未满足的需求。目前,德国缺乏经过评估的同伴支持干预措施。本研究旨在评估“Peer2Me”的有效性,这是一项为期三个月的一对一同伴指导计划,旨在提高YA-CS的自我效能感。

方法

本研究采用双中心综合队列设计,招募了在德国莱比锡和汉堡接受急性治疗的YA-CS(18至39岁),这些患者在过去六个月内被诊断出患有各种肿瘤。YA-CS根据偏好被分配到干预组(IG,接受同伴指导)和对照组(CG,常规护理)。在导师培训后,根据诊断、年龄和性别进行配对。YA-CS在基线(t1)、干预后(3个月后,t2)和干预后三个月(t3)完成问卷调查。主要结局是用一般自我效能量表(GSES)和癌症行为量表(CBI-B)测量的自我效能感。统计分析包括混合设计方差分析和协方差分析,并控制基线分数。

结果

在274名符合条件的YA-CS中,共有106名YA-CS(IG组:n = 77,CG组:n = 29)完成了研究。三分之二的YA-CS(66.7%)明确表示希望被分配到IG组。在应对行为方面存在基线差异,IG组得分较低,表明对支持的需求更高。协方差分析显示,从t1到t2(p = 0.897)或从t1到t3(p = 0.779),两组在平均GSES得分变化上没有组间效应。此外,从t1到t2(p = 0.903)或从t1到t3(p = 0.995),两组在平均CBI-B得分改善方面也没有显著差异。

结论

“Peer2Me”计划在急性治疗期间对提高YA-CS的自我效能感没有显著效果。尽管对同伴指导的兴趣很高,但与标准护理相比,该干预措施没有显示出可测量的益处。虽然支持需求很明显,但需要进一步研究以优化针对该群体的同伴干预措施。

试验注册

该研究于2022年2月4日在clinicaltrials.gov上进行了回顾性注册(NCT05336318)。

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