Chen I-Ning, Wang I-Te, Mu Hsueh-Yu, Qiu J-Timothy, Liu Wei-Min, Chang Ching-Wen, Chiu Yen-Hsieh
Department of Obstetrics and Gynecology, Taipei Medical University Hospital, Taipei 110301, Taiwan.
Department of Obstetrics and Gynecology, College of Medicine, Taipei Medical University, Taipei 110301, Taiwan.
Cancers (Basel). 2022 Apr 24;14(9):2117. doi: 10.3390/cancers14092117.
To compare the survival outcomes between minimally invasive surgery (MIS) and laparotomy radical hysterectomy in patients with early-stage cervical cancer.
We conducted a retrospective study involving women who received a radical hysterectomy for cervical cancer, stage IA1 with lymphovascular invasion, IA2, IB1, IB2, or IIA from 2008 to 2016. Clinicopathologic and perioperative outcomes were compared using appropriate statistical methodologies.
Oncologic survival outcomes were analyzed using the Kaplan-Meier method. Among the 105 cases identified, 58 (55.2%) and 47 (44.8%) women underwent MIS and open radical hysterectomy, respectively. Over a median follow-up period of 62 months, women who underwent MIS and open radical hysterectomy had a 5-year overall survival rate of 87.9% and 89.4% ( = 0.845) and a 5-year disease-free survival rate of 82.5% and 86.7% ( = 0.624), respectively.
For early-stage cervical cancer, patients who underwent MIS radical hysterectomy had survival outcomes that were comparable to those who underwent open surgery at our institute.
比较早期宫颈癌患者行微创手术（MIS）与开腹根治性子宫切除术的生存结局。
我们进行了一项回顾性研究，纳入了2008年至2016年间因宫颈癌（IA1期伴脉管浸润、IA2期、IB1期、IB2期或IIA期）接受根治性子宫切除术的女性。使用适当的统计方法比较临床病理和围手术期结局。
采用Kaplan-Meier法分析肿瘤生存结局。在105例确诊病例中，分别有58例（55.2%）和47例（44.8%）女性接受了MIS和开腹根治性子宫切除术。在中位随访期62个月时，接受MIS和开腹根治性子宫切除术的女性5年总生存率分别为87.9%和89.4%（P = 0.845），5年无病生存率分别为82.5%和86.7%（P = 0.624）。
对于早期宫颈癌，在我们研究所，接受MIS根治性子宫切除术的患者的生存结局与接受开放手术的患者相当。
