Aparicio Thomas, Pachev Atanas, Laurent-Puig Pierre, Svrcek Magali
Gastroenterology and Digestive Oncology, Saint Louis Hospital, Assistance Publique Hôpitaux de Paris (APHP), Université de Paris, 75010 Paris, France.
Radiology Department, Saint Louis Hospital, Assistance Publique Hôpitaux de Paris (APHP), Université de Paris, 75010 Paris, France.
Cancers (Basel). 2022 May 2;14(9):2268. doi: 10.3390/cancers14092268.
Adenocarcinomas of the small intestine are rare tumors but their incidence is increasing. There is a slight male predominance. The median age at diagnosis is the 6th decade. The most frequent primary location is the duodenum. There is no clearly identified environmental risk factor, but adenocarcinomas of the small intestine are associated in almost 20% of cases with predisposing diseases (Crohn's disease, Lynch syndrome, familial adenomatous polyposis, Peutz-Jeghers syndrome and celiac disease).
小肠腺癌是罕见肿瘤，但其发病率正在上升。男性略占优势。诊断时的中位年龄为60岁。最常见的原发部位是十二指肠。目前尚无明确确定的环境危险因素，但在近20%的病例中，小肠腺癌与易感疾病（克罗恩病、林奇综合征、家族性腺瘤性息肉病、黑斑息肉综合征和乳糜泻）有关。
