von Heijne G, Segrest J P
FEBS Lett. 1987 Mar 23;213(2):238-40. doi: 10.1016/0014-5793(87)81497-7.
We show that the N-terminal leader peptides from the bacterial membrane proteins bacteriorhodopsin and halorhodopsin can be expected to form amphipathic alpha-helics with a highly hydrophobic nonpolar face and a narrow, negatively charged polar face. This finding is discussed in terms of a model for the integration of these proteins into the bacterial membrane.
我们发现，细菌膜蛋白细菌视紫红质和嗜盐视紫红质的N端前导肽有望形成两亲性α螺旋，其具有高度疏水的非极性面和狭窄的带负电荷的极性面。根据这些蛋白质整合到细菌膜中的模型对这一发现进行了讨论。
