Faculty of Materials Engineering and Physics, Cracow University of Technology, Podchorążych Str. 1, 30-084 Krakow, Poland.
Faculty of Food Technology, University of Agriculture in Krakow, Balicka Str. 122, 30-149 Krakow, Poland.
Molecules. 2022 Apr 26;27(9):2775. doi: 10.3390/molecules27092775.
This paper summarises a little over 100 years of research on the synthesis and the photophysical and biological properties of 1-pyrazolo[3,4-]quinolines that was published in the years 1911-2021. The main methods of synthesis are described, which include Friedländer condensation, synthesis from anthranilic acid derivatives, multicomponent synthesis and others. The use of this class of compounds as potential fluorescent sensors and biologically active compounds is shown. This review intends to summarize the abovementioned aspects of 1-pyrazolo[3,4-]quinoline chemistry. Some of the results that are presented in this publication come from the laboratories of the authors of this review.
本文总结了 1911 年至 2021 年期间发表的关于 1-吡唑并[3,4-]喹啉的合成以及光物理和生物学性质的 100 多年研究。描述了主要的合成方法，包括 Friedländer 缩合、从邻氨基苯甲酸衍生物合成、多组分合成等。展示了此类化合物作为潜在荧光传感器和生物活性化合物的用途。本综述旨在总结 1-吡唑并[3,4-]喹啉化学的上述方面。本出版物中呈现的一些结果来自本文作者所在实验室。
