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在使用枸橼酸氯米芬治疗期间,通过口腔和阴道电测量预测排卵。

Prediction of ovulation with the use of oral and vaginal electrical measurements during treatment with clomiphene citrate.

作者信息

Fernando R S, Regas J, Betz G

出版信息

Fertil Steril. 1987 Mar;47(3):409-15. doi: 10.1016/s0015-0282(16)59046-3.

DOI:10.1016/s0015-0282(16)59046-3
PMID:3556619
Abstract

This study was undertaken to evaluate the usefulness of measuring salivary and vaginal electrical resistance in monitoring ovulation induced by clomiphene citrate (CC). Data from 28 cycles of 12 women treated with CC were compared with those of 18 cycles of 13 women who were ovulating spontaneously. Patterns of salivary readings in CC and spontaneous cycles were similar and showed a preovulatory peak 6.2 (mean) days before the luteinizing hormone peak. The trend in vaginal readings for CC cycles differed from that of spontaneous ovulations in that the values were depressed during and shortly after CC therapy. Occurrence of the periovulatory nadir and subsequent rise was common to both groups. The rise in vaginal readings CC cycles occurred within 24 hours of the luteinizing hormone peak in 88% of cases. Retrospective analysis showed that, based on this method, artificial insemination would have been timed appropriately in 25 of 27 cycles or in every cycle, depending on the protocol used. The results indicate that the method is equally useful for predicting and confirming ovulation in cycles in which CC was used to induce ovulation as it is in spontaneous cycles.

摘要

本研究旨在评估测量唾液和阴道电阻在监测枸橼酸氯米芬(CC)诱导排卵中的作用。将12名接受CC治疗的女性的28个周期的数据与13名自然排卵女性的18个周期的数据进行比较。CC周期和自然周期中唾液读数的模式相似,在促黄体生成素峰值前6.2(平均)天出现排卵前峰值。CC周期阴道读数的趋势与自然排卵不同,即在CC治疗期间及治疗后不久读数降低。两组均出现排卵前后最低点及随后的升高。在88%的CC周期病例中,阴道读数的升高发生在促黄体生成素峰值的24小时内。回顾性分析表明,基于该方法,根据所使用的方案,27个周期中的25个周期或每个周期的人工授精时间安排将是合适的。结果表明,该方法在预测和确认使用CC诱导排卵的周期中的排卵方面与自然周期同样有用。

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Prediction of ovulation with the use of oral and vaginal electrical measurements during treatment with clomiphene citrate.在使用枸橼酸氯米芬治疗期间,通过口腔和阴道电测量预测排卵。
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