Fernando R S, Regas J, Betz G
Zetek, Inc., Aurora, CO 80011.
Hum Reprod. 1988 May;3(4):419-24. doi: 10.1093/oxfordjournals.humrep.a136720.
Predicting ovulation is useful for managing the infertile patient and when done sufficiently in advance for fertility regulation by periodic abstinence. It has been reported that ovulation could be predicted by measurement of salivary and vaginal electrical resistance (SR and VR). These data from 32 menstrual cycles of 23 women were obtained to evaluate this technique. Data of 14 cycles were from subjects receiving clomiphene citrate (CC), while the others were from spontaneously ovulating subjects. A peak in SR was seen 5-7 days before the day of the LH peak in both natural and CC cycles. A correlation coefficient (r) of 0.94 was seen for the day of the SR peak and that of the LH peak. The SR trend was similar in both natural and CC cycles. VR in spontaneous cycles declined to a periovulatory nadir and then increased. The patterns of VR in CC cycles were similar except that values were initially depressed during and shortly after the end of CC therapy. Over 90% of VR increases were on the day of the LH peak and the day following. Results indicate that the method is useful for predicting ovulation in natural and CC cycles. Since the number of days by which ovulation is predicted exceeds the expected lifespan of spermatozoa in the female reproductive tract, the method also shows potential for use in natural family planning.
预测排卵对于管理不孕患者以及通过定期禁欲提前充分进行生育调节时非常有用。据报道，可通过测量唾液和阴道电阻（SR和VR）来预测排卵。获取了23名女性32个月经周期的数据以评估该技术。14个周期的数据来自接受枸橼酸氯米芬（CC）治疗的受试者，其余数据来自自然排卵的受试者。在自然周期和CC周期中，SR峰值均出现在LH峰值前5 - 7天。SR峰值日与LH峰值日的相关系数（r）为0.94。自然周期和CC周期中SR趋势相似。自发周期中的VR下降至排卵前最低点然后上升。CC周期中VR的模式相似，只是在CC治疗期间及结束后不久数值最初会降低。超过90%的VR升高发生在LH峰值日及随后一天。结果表明该方法对于预测自然周期和CC周期中的排卵是有用的。由于预测排卵的天数超过了精子在女性生殖道中的预期寿命，该方法在自然计划生育中也显示出应用潜力。
