Roncero Carlos, Pérez Joselín, Molina Jesús, Quintano José Antonio, Campuzano Ana Isabel, Pérez Javier, Miravitlles Marc
Psychiatric Service, University of Salamanca Health Care Complex, 37007 Salamanca, Spain.
Institute of Biomedicine of Salamanca (IBSAL), University of Salamanca, 37007 Salamanca, Spain.
J Clin Med. 2022 May 2;11(9):2558. doi: 10.3390/jcm11092558.
We aimed to examine the prevalence of suicidal ideation in patients with chronic obstructive pulmonary disease (COPD) and the association between demographic and clinical variables and the occurrence of suicidal thoughts. This was a cross-sectional study. Sociodemographic and clinical data were recorded, and questionnaires were used to assess depressive symptoms (Beck Depression Inventory), comorbidities (Charlson Index), cognitive performance (Mini Mental State Examination), and quality of life (EuroQoL-5 dimensions and CAT). Specific questions about suicide-related behavior were included. Multivariate logistic regression analysis identified the significant factors associated with previous suicidal ideation and suicide attempts. The analysis included 1190 subjects. The prevalence of suicidal ideation and suicide attempts were 12.1% and 2.5%, respectively. Severely depressed patients had the highest prevalence of suicide-related behavior. The adjusted logistic model identified factors significantly associated with suicidal ideation: sex (odds ratio (OR) for women vs. men = 2.722 (95% confidence interval (CI) = 1.771-4.183)), depression score (OR = 1.163 (95% IC = 1.127-1.200)), and Charlson Index (OR 1.228 (95% IC 1.082-1.394)). Suicidal ideation is common in COPD patients, especially in women. While addressing suicidal ideation and suicide prevention, clinicians should first consider the management of depressive symptomatology and the improvement of coping strategies.
我们旨在研究慢性阻塞性肺疾病（COPD）患者自杀意念的患病率，以及人口统计学和临床变量与自杀念头发生之间的关联。这是一项横断面研究。记录了社会人口统计学和临床数据，并使用问卷评估抑郁症状（贝克抑郁量表）、合并症（查尔森指数）、认知表现（简易精神状态检查表）和生活质量（欧洲五维健康量表和慢性阻塞性肺疾病评估测试）。问卷中包含了与自杀相关行为的具体问题。多因素逻辑回归分析确定了与既往自杀意念和自杀未遂相关的显著因素。该分析纳入了1190名受试者。自杀意念和自杀未遂的患病率分别为12.1%和2.5%。重度抑郁患者的自杀相关行为患病率最高。校正后的逻辑模型确定了与自杀意念显著相关的因素：性别（女性与男性的比值比（OR）=2.722（95%置信区间（CI）=1.771 - 4.183））、抑郁评分（OR = 1.163（95% IC = 1.127 - 1.200））和查尔森指数（OR 1.228（95% IC 1.082 - 1.394））。自杀意念在COPD患者中很常见，尤其是女性。在处理自杀意念和预防自杀时，临床医生应首先考虑对抑郁症状的管理和应对策略的改善。
