Research Institute for Health Sciences, Chiang Mai University, Chiang Mai, Thailand.
Faculty of Medicine, Chiang Mai University, Chiang Mai, Thailand.
AIDS Care. 2023 Mar;35(3):406-410. doi: 10.1080/09540121.2022.2075537. Epub 2022 May 13.
We assessed the quality of life and HIV adherence self-efficacy of adolescents and young adults (AYA) with perinatal HIV infection (PHIV). This cross-sectional study was conducted in Chiang Mai, Thailand. AYA-PHIV aged between 15 and 25 years were enrolled, who all were initiated on antiretroviral treatment as children. The World Health Organization-quality of life-BREF questionnaire and the HIV Treatment Adherence Self-Efficacy Scale (HIV-ASES) were administered. A total of 111 AYA-PHIV were included, including 52 (47%) females. Their median age was 20.2 ± 2.6 years. The overall QOL was rated as favorable (good or very good) by 59.4% of AYA-PHIV. The highest score was seen in the social relationships domain followed by the environmental health domain. Males had a significantly lower score in the psychological health domain than females ( = 0.018). Simple linear regression revealed a negative association between male sex, physical, and psychological health domain scores. The overall mean HIV-ASES score was 7.79 ± 1.96 out of 10, with a trend toward lower scores in males ( = 0.062), and a weak positive correlation with QOL. Our study documented worse QOL and lower HIV adherence self-efficacy in male AYA-PHIV. The findings call for the design of tailored male-focused interventions.
我们评估了围产期感染艾滋病毒（PHIV）的青少年和青年（AYA）的生活质量和艾滋病毒遵医自我效能。这项横断面研究在泰国清迈进行。招募了年龄在 15 至 25 岁之间的 AYA-PHIV，他们都是在儿童时期开始接受抗逆转录病毒治疗的。采用世界卫生组织生活质量简表（WHOQOL-BREF）和艾滋病毒治疗遵医自我效能量表（HIV-ASES）进行评估。共纳入 111 名 AYA-PHIV，其中 52 名（47%）为女性。他们的中位年龄为 20.2 ± 2.6 岁。59.4%的 AYA-PHIV 总体生活质量评定为良好（好或非常好）。AYA-PHIV 的社会关系领域得分最高，其次是环境卫生领域。男性在心理健康领域的得分明显低于女性（=0.018）。简单线性回归显示，男性的性别、身体和心理健康领域得分与生活质量呈负相关。HIV-ASES 的总体平均得分为 10 分中的 7.79 ± 1.96，男性得分较低（=0.062），与生活质量呈弱正相关。我们的研究记录了男性 AYA-PHIV 的生活质量更差和艾滋病毒遵医自我效能更低。这些发现呼吁设计针对男性的针对性干预措施。
