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左锁骨下动脉覆盖与创伤患者行胸主动脉腔内修复术后的神经缺损无关。

Left Subclavian Artery Coverage is Not Associated with Neurological Deficits in Trauma Patients Undergoing Thoracic Endovascular Repair.

机构信息

Division of Vascular Surgery, Department of Surgery, University of Rochester Medical Center, Rochester, NY.

Division of Vascular Surgery, Department of Surgery, University of Rochester Medical Center, Rochester, NY.

出版信息

Ann Vasc Surg. 2022 Oct;86:408-416. doi: 10.1016/j.avsg.2022.04.050. Epub 2022 May 12.

Abstract

BACKGROUND

Endovascular repair of the thoracic aorta (TEVAR) outcomes have been studied with an interest in complications related to left subclavian artery (LSA) coverage in patients with atherosclerotic pathologies; however, specific data on the management of the LSA in a trauma population are lacking. The objective of this study is to evaluate outcomes following TEVAR for traumatic aortic injury based on LSA coverage.

METHODS

The Vascular Quality Initiative thoracic endovascular aortic repair module (2010-2017) was analyzed. Patients were included if they had a traumatic aortic injury requiring TEVAR. Patients were placed in 2 groups based on coverage of the LSA. Patients were propensity score matched and the primary outcomes were cerebrovascular symptoms and spinal cord ischemia. Additional clinical and resource utilization outcomes were analyzed.

RESULTS

Four hundred and fifty one patients were included in the analysis. There were 268 patients in the LSA not-covered group and 183 patients in the LSA covered group. The mean aortic injury grade was 2.88 ± 0.056 vs. 2.88 ± 0.049 in the covered versus not-covered group (P = 0.957). Glasgow coma scale and injury severity score were not different between the groups. There was no difference between groups for cerebrovascular symptoms or spinal cord ischemia, 1.4% vs. 2.8%, P = 0.684 and 0% vs. 2.1%, P = 0.247, after propensity score matching. Significant differences in access site complications and resource utilization were identified between groups.

CONCLUSIONS

This is the largest series to evaluate complications based on LSA coverage following TEVAR in trauma patients. Our data demonstrate that coverage of the LSA during TEVAR following blunt trauma is associated with no difference in central nervous system outcomes. As such, LSA revascularization strategies, while possible, are not directly supported by these data and should be individualized based on each patient's specific clinical scenario.

摘要

背景

血管内修复胸主动脉(TEVAR)的结果已被研究,重点关注动脉粥样硬化病变患者左锁骨下动脉(LSA)覆盖相关的并发症;然而,创伤人群中 LSA 管理的具体数据仍然缺乏。本研究旨在评估基于 LSA 覆盖的 TEVAR 治疗创伤性主动脉损伤的结果。

方法

分析血管质量倡议胸主动脉腔内修复模块(2010-2017 年)。纳入标准为需要 TEVAR 治疗的创伤性主动脉损伤患者。根据 LSA 的覆盖情况将患者分为两组。对患者进行倾向评分匹配,主要结局为脑血管症状和脊髓缺血。分析了其他临床和资源利用结局。

结果

共纳入 451 例患者。其中,未覆盖 LSA 组 268 例,覆盖 LSA 组 183 例。平均主动脉损伤等级为 2.88±0.056 vs. 2.88±0.049 在覆盖组和未覆盖组(P=0.957)。格拉斯哥昏迷评分和损伤严重程度评分在两组间无差异。在未覆盖组和覆盖组中,脑血管症状或脊髓缺血的发生率无差异,分别为 1.4%vs.2.8%,P=0.684 和 0%vs.2.1%,P=0.247,在倾向评分匹配后。两组间在入路部位并发症和资源利用方面存在显著差异。

结论

这是评估创伤患者 TEVAR 后基于 LSA 覆盖的并发症的最大系列研究。我们的数据表明,钝性创伤后 TEVAR 时 LSA 的覆盖与中枢神经系统结局无差异。因此,LSA 血运重建策略虽然可能,但这些数据并未直接支持,应根据每个患者的具体临床情况个体化。

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