Department of Surgery, Division of Vascular and Endovascular Surgery, Stony Brook Medicine, Stony Brook, NY.
Department of Surgery, Division of Vascular and Endovascular Surgery, Stony Brook Medicine, Stony Brook, NY.
J Vasc Surg. 2018 Oct;68(4):985-990. doi: 10.1016/j.jvs.2018.01.046. Epub 2018 May 18.
Thoracic endovascular aortic repair (TEVAR) is the standard treatment of blunt thoracic aortic injury (BTAI). The concept of seal was derived from the treatment of aneurysms and has been adopted for BTAI. Given the location of injury in BTAI, left subclavian artery (LSA) coverage is sometimes necessary. In these often healthier aortas, a shorter proximal landing zone may be acceptable and beneficial in avoiding some complications. Current practice patterns vary, and long-term effects of LSA coverage remain unknown.
A single-institution experience with BTAI for TEVAR was examined from 2006 to 2017. The primary outcome was failure of sealing, endoleak, or persistent aortic injury on follow-up imaging. A centerline was used to measure the length of the landing zone, aortic diameter, and other parameters. Post-TEVAR computed tomography scans were examined for evidence of residual aortic injury.
A total of 30 TEVARs were performed for BTAI. The mean age of the patients was 38.7 years (standard deviation [SD], 19.8 years), and 70% were male. The mean injury severity score was 36.75 (SD, 13.1). Treated patients had grade 2 (36.7%) or grade 3 (63.3%) BTAI. The LSA was salvaged in 23 cases and covered in seven cases. The mean landing zone in LSA uncovered cases was 16 mm (SD, 10.4 mm). There were 15 patients (65%) who had a landing zone <20 mm, and eight (35%) patients had a landing zone >20 mm. The mean landing zone in the seven covered cases was 1.8 mm (SD, 2.4 mm). Procedural success was 96% for the uncovered group and 100% for the covered group. On follow-up imaging, there was only one residual endoleak in all surviving patients (n = 25). Five patients did not have postoperative imaging, two (7%) of whom died of nonaorta-related issues.
TEVAR for BTAI in patients with short proximal landing zones of 10 to 20 mm as well as in select patients with landing zones of 5 to 10 mm appears to be safe and efficacious. The aorta demonstrates no residual injury after TEVAR, with the graft acting potentially more as a bridge to allow healing. Long-term issues regarding LSA coverage have been difficult to ascertain and to evaluate because of historically poor follow-up in this population of patients. However, potential issues with LSA coverage and revascularization may be avoided by preserving the subclavian artery even with shorter proximal landing zones.
胸主动脉腔内修复术(TEVAR)是治疗钝性胸主动脉损伤(BTAI)的标准治疗方法。密封的概念源自于对动脉瘤的治疗,并已被用于 BTAI。鉴于 BTAI 的损伤位置,有时需要覆盖左锁骨下动脉(LSA)。在这些通常更健康的主动脉中,较短的近端着陆区可能是可以接受的,并且有利于避免一些并发症。目前的实践模式存在差异,LSA 覆盖的长期影响仍不清楚。
对 2006 年至 2017 年期间因 TEVAR 治疗的 BTAI 进行了单中心回顾性研究。主要结果是随访影像学检查显示密封失败、内漏或持续性主动脉损伤。使用中心线测量着陆区长度、主动脉直径和其他参数。对 TEVAR 后的计算机断层扫描(CT)进行检查,以观察是否存在残余主动脉损伤。
共对 30 例 BTAI 患者进行了 30 例 TEVAR 治疗。患者的平均年龄为 38.7 岁(标准差[SD],19.8 岁),70%为男性。平均损伤严重程度评分为 36.75(SD,13.1)。治疗患者的 BTAI 分级为 2 级(36.7%)或 3 级(63.3%)。23 例患者挽救了 LSA,7 例患者覆盖了 LSA。在未覆盖 LSA 的病例中,平均着陆区为 16 毫米(SD,10.4 毫米)。有 15 例(65%)患者的着陆区<20 毫米,8 例(35%)患者的着陆区>20 毫米。在 7 例覆盖 LSA 的病例中,平均着陆区为 1.8 毫米(SD,2.4 毫米)。未覆盖组的手术成功率为 96%,覆盖组为 100%。在所有存活患者(n=25)的随访影像学检查中,只有 1 例存在残余内漏。5 例患者未行术后影像学检查,其中 2 例(7%)死于非主动脉相关问题。
对于近端着陆区为 10 至 20 毫米的 BTAI 患者,以及近端着陆区为 5 至 10 毫米的特定患者,TEVAR 似乎是安全有效的。TEVAR 后主动脉无残余损伤,移植物可能更像一座桥梁,允许愈合。由于历史上对该患者群体的随访不佳,LSA 覆盖的长期问题一直难以确定和评估。然而,通过保留锁骨下动脉,即使近端着陆区较短,也可能避免 LSA 覆盖和再血管化的潜在问题。