Uveitis and Ocular Immunology, Narayana Nethralaya, Bangalore, Karnataka, India
Uveitis and Ocular Immunology, Narayana Nethralaya, Bangalore, Karnataka, India.
BMJ Case Rep. 2022 May 13;15(5):e248415. doi: 10.1136/bcr-2021-248415.
A woman in her 50s presented with diminution of vision in her left eye (OS) 4 days after COVISHIELD vaccination. She had been diagnosed with non-arteritic anterior ischaemic optic neuropathy (NA-AION) of right eye (OD) 8 months earlier. The present episode revealed a best-corrected visual acuity (BCVA) of 20/50 in OD and 20/20 in OS with grade 1 relative afferent pupillary defect. Fundus evaluation showed pale disc in OD and temporal disc oedema in OS. Humphrey's visual field analysis showed incomplete inferior altitudinal defect in OD and a centro-caecal scotoma in OS. Systemic investigations were normal. OS was diagnosed with NA-AION. She was started on oral aspirin 75 mg. At 1-month follow-up, disc oedema of OS had resolved with BCVA maintaining at 20/20. The patient was lost to follow-up later. The relationship between the vaccine and the ocular event is temporal with no causal association.
一位 50 多岁女性，在接种 COVISHIELD 疫苗后 4 天出现左眼（OS）视力下降。她曾于 8 个月前被诊断为右眼（OD）非动脉炎性前部缺血性视神经病变（NA-AION）。本次发病时，OD 的最佳矫正视力（BCVA）为 20/50，OS 的 BCVA 为 20/20，伴有 1 级相对传入瞳孔缺陷。眼底检查显示 OD 视盘苍白，OS 视盘颞侧水肿。Humphrey 视野分析显示 OD 存在不完全性下垂直缺损，OS 存在中心-囊样暗点。全身检查正常。OS 被诊断为 NA-AION。给予她口服阿司匹林 75mg。在 1 个月的随访中，OS 的视盘水肿已消退，BCVA 保持在 20/20。后来，该患者失访。疫苗与眼部事件之间存在时间关系，但没有因果关联。
