真核生物翻译起始因子4E（eIF4E）与eIF4E相互作用蛋白之间的多种关系。
The versatile relationships between eIF4E and eIF4E-interacting proteins.
作者信息
Hernández Greco
机构信息
Translation and Cancer Laboratory, Unit of Biomedical Research on Cancer, National Institute of Cancer (Instituto Nacional de Cancerología, INCan). 22 San Fernando Avenue, Tlalpan, 14080-Mexico City, Mexico.
出版信息
Trends Genet. 2022 Aug;38(8):801-804. doi: 10.1016/j.tig.2022.04.003. Epub 2022 May 11.
RNA metabolism and gene expression lie at the core of cellular life. eIF4E has emerged as a central interface in both processes as it plays critical roles in mRNA processing, transport, translation, and storage. Crucially, eIF4E depends on its association with a universe of proteins to form biologically meaningful complexes.
RNA代谢和基因表达是细胞生命的核心。真核起始因子4E（eIF4E）已成为这两个过程的核心界面，因为它在mRNA加工、运输、翻译和储存中发挥着关键作用。至关重要的是，eIF4E依赖于与众多蛋白质的结合来形成具有生物学意义的复合物。
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