Hernández Greco
Translation and Cancer Laboratory, Unit of Biomedical Research on Cancer, National Institute of Cancer (Instituto Nacional de Cancerología, INCan). 22 San Fernando Avenue, Tlalpan, 14080-Mexico City, Mexico.
Trends Genet. 2022 Aug;38(8):801-804. doi: 10.1016/j.tig.2022.04.003. Epub 2022 May 11.
RNA metabolism and gene expression lie at the core of cellular life. eIF4E has emerged as a central interface in both processes as it plays critical roles in mRNA processing, transport, translation, and storage. Crucially, eIF4E depends on its association with a universe of proteins to form biologically meaningful complexes.
RNA代谢和基因表达是细胞生命的核心。真核起始因子4E（eIF4E）已成为这两个过程的核心界面，因为它在mRNA加工、运输、翻译和储存中发挥着关键作用。至关重要的是，eIF4E依赖于与众多蛋白质的结合来形成具有生物学意义的复合物。
