Rush University Medical Center, Chicago, IL, 60612, United States.
Inova Children's Hospital, Falls Church, VA, 22042, United States.
Semin Fetal Neonatal Med. 2022 Aug;27(4):101348. doi: 10.1016/j.siny.2022.101348. Epub 2022 Apr 22.
Pulmonary hypertension (PH) is an important and potentially lethal diagnosis for pregnant patients. Although pregnancy is usually contraindicated in this condition and there is no standard algorithm for the treatment of pregnant patients with PH, studies in recent years have shown improvement in maternal outcomes for those with PH. Many factors have likely contributed to the improved outcomes, including earlier treatment by multidisciplinary teams. Pregnant patients with PH require specialized management throughout pregnancy, especially in the early post-partum period. Echocardiography is an important diagnostic tool to follow cardiac function in these patients. PH and its treatment during pregnancy has significant implications on maternal as well as fetal outcomes. In this review, PH management during pregnancy and the fetal implications are summarized.
肺动脉高压(PH)是孕妇的一个重要且潜在致命的诊断。尽管在这种情况下通常不建议怀孕,并且对于患有 PH 的孕妇也没有标准的治疗算法,但近年来的研究表明,患有 PH 的孕妇的母婴结局有所改善。许多因素可能促成了这些改善的结果,包括多学科团队的早期治疗。患有 PH 的孕妇在整个怀孕期间需要专门的管理,尤其是在产后早期。超声心动图是监测这些患者心功能的重要诊断工具。PH 及其在怀孕期间的治疗对母婴结局都有重要影响。在这篇综述中,总结了怀孕期间 PH 的管理及其对胎儿的影响。