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米诺环素成功治疗肾移植患者的星形诺卡菌感染。

Successful treatment of Nocardia asteroides infection with minocycline in kidney transplant patients.

作者信息

Ochiai T, Amemiya H, Watanabe K, Sato H, Kobayashi A, Takizawa H, Iwasaki Y

出版信息

Jpn J Surg. 1978 Jun;8(2):138-44. doi: 10.1007/BF02469369.

DOI:10.1007/BF02469369
PMID:355687
Abstract

Two cases of Noca dia asteroides infection were encountered out of 55 kidney transplant patients at Chiba University Hospital. One patient developed an extrapleural abscess and the other had a pulmonary infiltration with chest wall abscess. The patients were successfully treated by surgical drainage of the chest wall abscesses and by oral administration of minocycline. No adverse effects caused by minocycline were observed during the therapy. From 1900, when the first case of Nocardia infection was reported in Japan, there have been 60 cases reported in Japanese literature through 1973, including those we observed. This is the first report on nocardiosis in kidney transplant patients and on successful treatment of nocardiosis with minocycline in Japan.

摘要

在千叶大学医院的55例肾移植患者中,发现了2例星形诺卡菌感染病例。1例患者发生了胸膜外脓肿,另1例有肺部浸润伴胸壁脓肿。通过胸壁脓肿的外科引流和口服米诺环素,患者得到了成功治疗。治疗期间未观察到米诺环素引起的不良反应。自1900年日本报道首例诺卡菌感染病例以来,至1973年日本文献中已报道了60例,包括我们观察到的病例。这是日本关于肾移植患者诺卡菌病及米诺环素成功治疗诺卡菌病的首例报告。

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本文引用的文献

1
NOCARDIOSIS AND PULMONARY ALVEOLAR PROTEINOSIS.诺卡菌病与肺泡蛋白沉积症
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Nocardiosis in anaemic patients given steroids.接受类固醇治疗的贫血患者中的诺卡菌病。
J Clin Pathol. 1961 May;14(3):259-63. doi: 10.1136/jcp.14.3.259.
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The changing spectrum of nocardiosis. A review and presentation of nine cases.
Am Rev Respir Dis. 1961 Mar;83:315-30. doi: 10.1164/arrd.1961.83.3.315.
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Nocardia infections in a general hospital.综合医院中的诺卡菌感染
Ann N Y Acad Sci. 1970 Oct 30;174(2):552-67. doi: 10.1111/j.1749-6632.1970.tb45581.x.
5
Systemic fungal infections complicating renal transplantation and immunosuppressive therapy. Clinical, microbiologic, neurologic and pathologic features.并发肾移植及免疫抑制治疗的系统性真菌感染。临床、微生物学、神经学及病理学特征。
Am J Med. 1967 Jul;43(1):28-38. doi: 10.1016/0002-9343(67)90146-5.
6
Nocardia asteroides infection complicating neoplastic disease.星形诺卡菌感染并发肿瘤性疾病。
Am J Med. 1971 Mar;50(3):356-67. doi: 10.1016/0002-9343(71)90224-5.
7
Antimicrobial susceptibility of Nocardia species.诺卡菌属的抗菌药敏性。
Antimicrob Agents Chemother. 1973 Aug;4(2):85-93. doi: 10.1128/AAC.4.2.85.
8
Diagnostic and therapeutic considerations in Nocardia asteroides infection.星形诺卡菌感染的诊断与治疗考量
Medicine (Baltimore). 1974 Sep;53(5):391-401. doi: 10.1097/00005792-197409000-00005.
9
Susceptibility of Nocardia asteroides to 45 antimicrobial agents in vitro.星形诺卡菌对45种抗菌药物的体外敏感性
Antimicrob Agents Chemother. 1973 Jan;3(1):1-8. doi: 10.1128/AAC.3.1.1.
10
Pulmonary nocardiosis. Therapy with minocycline and with erythromycin plus ampicillin.肺诺卡菌病。米诺环素以及红霉素加氨苄西林治疗。
JAMA. 1973 Jun 4;224(10):1378-81. doi: 10.1001/jama.224.10.1378.