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[肥厚型心肌病与青少年猝死。一例临床病例及对该问题的重新评估]

[Hypertrophic cardiomyopathy and juvenile sudden death. A clinical case and re-evaluation of the problem].

作者信息

Corrado D, Carraro R, Buja G, Fasoli G, Thiene G

出版信息

G Ital Cardiol. 1986 Dec;16(12):1002-8.

PMID:3556936
Abstract

A 29-year-old man with non-familiar hypertrophic cardiomyopathy died suddenly. The patient experienced recurrent episodes of palpitation both at rest and during exercise. M-mode and 2-D echocardiograms showed severe asymmetric septal hypertrophy (IVS/LVPW ratio 3:1) and systolic anterior motion of anterior leaflet of the mitral valve. The ECG demonstrated deep "Q" waves from the inferior leads and inverted "T" waves in V1 to V6, but failed to register arrhythmias. Holter monitoring had been planned in order to achieve information for pharmacologic therapy, but unfortunately the patient died during the stand-by. Postmortem examination showed severe asymmetric septal hypertrophy with fibrosis and wide-spread "myocardial disarray".

摘要

一名29岁的非家族性肥厚型心肌病男性突然死亡。该患者在休息和运动时均反复出现心悸发作。M型和二维超声心动图显示严重的不对称性室间隔肥厚(室间隔/左室后壁厚度比值为3:1)以及二尖瓣前叶收缩期前向运动。心电图显示下壁导联有深“Q”波,V1至V6导联T波倒置,但未记录到心律失常。原本计划进行动态心电图监测以获取药物治疗的相关信息,但不幸的是,患者在等待过程中死亡。尸检显示严重的不对称性室间隔肥厚伴纤维化和广泛的“心肌紊乱”。

相似文献

1
[Hypertrophic cardiomyopathy and juvenile sudden death. A clinical case and re-evaluation of the problem].[肥厚型心肌病与青少年猝死。一例临床病例及对该问题的重新评估]
G Ital Cardiol. 1986 Dec;16(12):1002-8.
2
[Apical hypertrophy as a part of the morphologic spectrum of hypertrophic cardiomyopathy].[心尖肥厚作为肥厚型心肌病形态学谱的一部分]
J Cardiogr. 1984 Aug;14(2):289-300.
3
[Malignant familial cardiomyopathy with sudden death, typical asymmetric septal hypertrophy and dilated cardiomyopathy-like features].[伴有猝死的恶性家族性心肌病、典型的不对称性室间隔肥厚及扩张型心肌病样特征]
J Cardiogr. 1986 Mar;16(1):81-94.
4
[Hypertrophic cardiomyopathy with dilatation of the left ventricle and congestive heart failure: comparison with postmyocarditis cardiomegaly and hypertensive heart failure].[伴有左心室扩张和充血性心力衰竭的肥厚型心肌病:与心肌炎后心脏扩大和高血压性心力衰竭的比较]
J Cardiogr. 1983 Sep;13(3):537-50.
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[Sudden death and obstructive hypertrophic cardiomyopathy].[猝死与梗阻性肥厚型心肌病]
Ann Cardiol Angeiol (Paris). 1985 Mar;34(3):155-60.
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[Hemodynamic and electrophysiologic changes in hypertrophic cardiomyopathy].
Rev Esp Cardiol. 1996 Jan;49(1):56-68.
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Hypertrophic cardiomyopathy with dominant hypertrophy in the right anterobasal region of the ventricular septum: a case report.肥厚型心肌病,以室间隔右前基底区域为主的肥厚:一例报告
J Cardiol. 2000 Jul;36(1):45-8.
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[Hypertrophic cardiomyopathy with progressive left ventricular hypertrophy: a case report].[肥厚型心肌病伴进行性左心室肥厚:一例报告]
J Cardiogr. 1985 Mar;15(1):249-60.
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Hypertrophic cardiomyopathy and sudden death in the young: pathologic evidence of myocardial ischemia.肥厚型心肌病与年轻人猝死:心肌缺血的病理证据
Hum Pathol. 2000 Aug;31(8):988-98. doi: 10.1053/hupa.2000.16659.
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[Diagnosis of nonobstructive hypertrophic cardiomyopathy in a patient with Down's syndrome].
Minerva Cardioangiol. 1994 Nov;42(11):549-51.

引用本文的文献

1
Should lethal arrhythmias in hypertrophic cardiomyopathy be predicted using non-electrophysiological methods?肥厚型心肌病中致死性心律失常是否可以通过非电生理方法预测?
Europace. 2023 May 19;25(5). doi: 10.1093/europace/euad045.