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远紫外线C对产超广谱β-内酰胺酶大肠杆菌的杀菌作用。

The bactericidal effect of far-UVC on ESBL-producing Escherichia coli.

作者信息

Fukuda Soichiro, Nishikawa Jun, Kobayashi Yuki, Okabe Yumi, Fujii Tomohiro, Kubota Naoto, Otsuyama Ken-Ichiro, Tsuneoka Hidehiro, Hashimoto Shinichi, Suehiro Yutaka, Yamasaki Takahiro, Takami Taro

机构信息

Faculty of Laboratory Science, Yamaguchi University Graduate School of Medicine, Ube, Japan.

Faculty of Laboratory Science, Yamaguchi University Graduate School of Medicine, Ube, Japan.

出版信息

Am J Infect Control. 2022 Nov;50(11):1268-1270. doi: 10.1016/j.ajic.2022.04.012. Epub 2022 May 13.

Abstract

Because extended-spectrum beta-lactamase (ESBL) infections can cause life-threatening disease and effective treatments need to be developed, we examined the bactericidal effect of far-ultraviolet C (far-UVC) light therapy on ESBL-producing Escherichia coli (E. coli). The bactericidal effect on 2 types of ESBL-producing E. coli was the same as that on the wild strain although the results of drug resistance tests varied among these strains. We believe that irradiation with far-UVC is effective in preventing infection by ESBL-producing E. coli in health care settings.

摘要

由于超广谱β-内酰胺酶(ESBL)感染可导致危及生命的疾病,且需要开发有效的治疗方法,我们研究了远紫外线C(far-UVC)光疗法对产ESBL的大肠杆菌的杀菌作用。尽管这些菌株的耐药性测试结果各不相同,但远紫外线C对两种产ESBL的大肠杆菌的杀菌效果与对野生菌株的杀菌效果相同。我们认为,在医疗环境中,用远紫外线C照射可有效预防产ESBL的大肠杆菌感染。

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