Gan Bin, Liu Siyang, Wu Yilong
Lung Cancer Institute, Guangdong Provincial Key Laboratory of Translational Medicine in Lung Cancer, Guangdong Provincial People's Hospital, Guangdong Academy of Medical Sciences, Guangzhou 510080, China.
Department of Hematology, The First Affiliated Hospital of Jinan University; Hematology Institute, Jinan University Faculty of Medical Science; Key Laboratory for Regenerative Medicine, Ministry of Education, Guangzhou 510632, China.
Zhongguo Fei Ai Za Zhi. 2022 May 20;25(5):295-302. doi: 10.3779/j.issn.1009-3419.2022.101.19. Epub 2022 May 16.
Though the coronavirus disease is still raging in 2021, clinical research on non-small cell lung cancer (NSCLC) did not stop. However, benefiting from advances in lung cancer treatment modality, NSCLC patients have experienced significant improvements in overall survival and quality of life. Currently, research advances on targeted therapy and immunotherapy have together transformed the status of postoperative adjuvant therapy and established a new standard treatment modality for resectable NSCLC. There are equally important research advances in locally advanced and advanced NSCLC, including new treatment modalities, new therapeutic agents, etc., all of which bringing more options for clinical treatment. These therapies will bring changes to NSCLC and will gradually lead to the chronicity of lung cancer in the foreseeable future. Therefore, this paper reviews important studies that will change clinical practice in NSCLC treatment and noteworthy research advances in 2021. .
尽管2021年冠状病毒病仍在肆虐,但非小细胞肺癌(NSCLC)的临床研究并未停止。然而,受益于肺癌治疗方式的进步,NSCLC患者的总生存期和生活质量有了显著改善。目前,靶向治疗和免疫治疗的研究进展共同改变了术后辅助治疗的现状,并为可切除的NSCLC建立了新的标准治疗模式。局部晚期和晚期NSCLC也有同样重要的研究进展,包括新的治疗模式、新的治疗药物等,所有这些都为临床治疗带来了更多选择。这些疗法将给NSCLC带来改变,并在可预见的未来逐渐导致肺癌的慢性化。因此,本文综述了将改变NSCLC治疗临床实践的重要研究以及2021年值得关注的研究进展。