Servicio de Farmacología Clínica, Hospital Universitario Puerta de Hierro, Instituto de Investigación Sanitaria Puerta de Hierro-Segovia de Arana, Majadahonda, Madrid, Spain.
Unidad de Toxicología Clínica, Servicio de Urgencias, Hospital Universitario Son Espases, Palma de Mallorca, Spain.
Rev Clin Esp (Barc). 2022 Aug-Sep;222(7):406-411. doi: 10.1016/j.rceng.2022.02.004. Epub 2022 May 13.
The COVID-19 pandemic has caused global changes that affect the daily life of the world's population, with a direct impact on individuals' physical and mental health as well as on their social and recreational habits.
This study aimed to retrospectively analyze the demographic and clinical characteristics of patients attended to for acute poisoning in a hospital emergency department (ED) at three different periods of time: pre-pandemic (2019), after strict lockdown of the population in Spain (2020), and post-pandemic (2021). We analyzed 2 months (June and July) in each period.
A total of 1,182 cases of acute poisoning were included. Compared to the pre-pandemic period, during lockdown, the number of patients with acute poisoning decreased (2019: 1.9% vs. 2020: 1.5%; p < 0.01); the ratio of men to women increased (2.0 vs. 1.4; p = 0.02); and the mean age of patients increased (2019: 31.4 vs. 2020: 41.3; p < 0.001), a trend which continued in 2021 (38.3). Poisoning with suicidal intention also increased during the pandemic (2019: 8.71% vs. 2020: 21.0%; p < 0.01) whereas poisonings with a recreational intention declined (2019: 76.1% vs. 2020: 62.0%; p < 0.01) with a non-significant increase in 2021 (69.0%, p = 0.07).
The COVID-19 pandemic generated clinical and epidemiological changes in the acute poisonings attended to in a hospital emergency department during the various phases of the pandemic.
COVID-19 大流行导致了全球变化，影响了世界人口的日常生活，直接影响了个人的身心健康以及他们的社会和娱乐习惯。
本研究旨在回顾性分析在医院急诊科就诊的急性中毒患者的人口统计学和临床特征，该研究在三个不同时期进行：大流行前（2019 年）、西班牙人口严格封锁后（2020 年）和大流行后（2021 年）。我们分析了每个时期的 2 个月（6 月和 7 月）。
共纳入 1182 例急性中毒病例。与大流行前相比，在封锁期间，急性中毒患者数量减少（2019 年：1.9%比 2020 年：1.5%；p<0.01）；男女比例增加（2.0 比 1.4；p=0.02）；患者的平均年龄增加（2019 年：31.4 比 2020 年：41.3；p<0.001），这种趋势在 2021 年仍在继续（38.3）。自杀意图中毒在大流行期间也有所增加（2019 年：8.71%比 2020 年：21.0%；p<0.01），而娱乐意图中毒则下降（2019 年：76.1%比 2020 年：62.0%；p<0.01），2021 年虽有非显著性增加（69.0%，p=0.07）。
COVID-19 大流行在大流行的各个阶段在医院急诊科就诊的急性中毒患者中产生了临床和流行病学变化。
