Anzai Yuzuru, Cercizi Noel, Wu Yifei, Park Crystal, Sefah Narvella, Gomez Isabella, Yao Nicole, Gulati Jasmine, Lee Seoho, McClelland W Spencer, Cheon Teresa, Benedetto-Anzai Maria Teresa, Chervenak Francis A
Department of Obstetrics and Gynecology, Lenox Hill Hospital/Donald and Barbara Zucker School of Medicine at Hofstra/Northwell, New York, NY, USA.
University of Chicago, Chicago, IL, USA.
J Perinat Med. 2022 May 17;50(8):1030-1035. doi: 10.1515/jpm-2022-0084. Print 2022 Oct 26.
To determine the racial and ethnic compositions of the participants in obstetric randomized controlled trials (RCTs) and compare them to the US general population.
RCTs published in two premier US journals, Gynecology from January 2010 to April 2020 were analyzed. The racial and ethnic distributions of the study participants were extracted and expressed as percentages for each article. Obstetrics articles were selected and then further divided into subcategories. Statistical analyses were performed on racial and ethnicity representation in each subcategory compared to a US population norm.
Overall, a wide variation of racial and ethnic distribution was noted among studies. However, statistically significant overrepresentation of Non-Hispanic Black population and underrepresentation of White and Asian races were noted while Hispanic population's representation was comparable to the US general population. This observation was persistent across most of the subcategories.
RCTs in the field of Obstetrics showed an overrepresentation of Black population. This observation was unique when we consider the previous reports in other fields of medicine. These findings should be taken into consideration when interpreting the results of RCTs conducted in US.
确定产科随机对照试验（RCT）参与者的种族和族裔构成，并将其与美国普通人群进行比较。
分析2010年1月至2020年4月在美国两份顶级期刊《妇产科学》上发表的随机对照试验。提取研究参与者的种族和族裔分布，并以每篇文章的百分比表示。选择产科文章，然后进一步细分为子类别。与美国人口标准相比，对每个子类别中的种族和族裔代表性进行统计分析。
总体而言，各研究之间的种族和族裔分布差异很大。然而，非西班牙裔黑人人口的比例在统计学上显著过高，白人和亚洲种族的比例过低，而西班牙裔人口的比例与美国普通人群相当。这一观察结果在大多数子类别中都持续存在。
产科领域的随机对照试验显示黑人人口比例过高。当我们考虑医学其他领域的先前报告时，这一观察结果是独特的。在美国进行随机对照试验结果解释时应考虑这些发现。
