Menakuru Sasmith R, Priscu Adelina, Dhillon Vijaypal, Salih Ahmed
Internal Medicine, Indiana University Health, Ball Memorial Hospital, Muncie, IN 47303, USA.
J Hematol. 2022 Apr;11(2):62-65. doi: 10.14740/jh964. Epub 2022 Mar 12.
Cyclical thrombocytopenia (CTP) is a very rare condition and often misdiagnosed as immune thrombocytopenia (ITP) due to similar features existing between the two. When evaluating a patient for the possible diagnosis of ITP, CTP must be high on the differential diagnosis. The main difference between the two conditions is that CTP is usually unresponsive to the treatment given to ITP and will ultimately display a cyclical nature with periods of low, normal and elevated platelets. As of date, there are only 70 cases in the literature. However, this number may be misrepresented due to the difficulty in diagnosis. The authors report a case of a 36-year-old woman who was misdiagnosed with ITP and underwent unnecessary treatment with corticosteroids, rituximab, intravenous immunoglobulins, and a splenectomy. A diagnosis of CTP was made after extensive review and the authors aim to bring awareness of this uncommon condition.
周期性血小板减少症（CTP）是一种非常罕见的病症，由于两者存在相似特征，常被误诊为免疫性血小板减少症（ITP）。在评估患者是否可能患有ITP时，CTP必须在鉴别诊断中被高度考虑。这两种病症的主要区别在于，CTP通常对给予ITP的治疗无反应，最终会呈现出周期性，血小板水平会出现低、正常和升高的阶段。截至目前，文献中仅有70例病例。然而，由于诊断困难，这个数字可能存在偏差。作者报告了一例36岁女性，她被误诊为ITP，并接受了不必要的皮质类固醇、利妥昔单抗、静脉注射免疫球蛋白和脾切除术治疗。经过广泛审查后确诊为CTP，作者旨在提高对这种罕见病症的认识。
