生长抑素与糖尿病

Somatostatin and diabetes.

作者信息

Rizza R A, Gerich J E

出版信息

Med Clin North Am. 1978 Jul;62(4):735-46. doi: 10.1016/s0025-7125(16)31769-2.

Abstract

Somatostatin may act as a local regulator of endocrine and exocrine secretion and as a peptidergic neurotransmitter rather than as a classical circulating hormone. The possible physiologic role of its secretion in the regulation of islet A and B cell function, and particularly its significance in nutrient homeostasis and diabetes, are discussed.

摘要

生长抑素可能作为内分泌和外分泌分泌的局部调节剂以及肽能神经递质，而不是作为经典的循环激素。本文讨论了其分泌在调节胰岛A细胞和B细胞功能中的可能生理作用，特别是其在营养稳态和糖尿病中的意义。