Food Animal Environmental Systems Research Unit, Agricultural Research Service, United States Department of Agriculture (USDA), Bowling Green, Kentucky, USA.
Utah Water Research Laboratory, Department of Civil and Environmental Engineering, Utah State University, Logan, Utah, USA.
Microb Drug Resist. 2022 Jun;28(6):734-743. doi: 10.1089/mdr.2021.0438. Epub 2022 May 16.
species are a normal flora of animals and humans. However, life-threatening opportunistic infections can be caused by antimicrobial resistant strains. Fecal ( = 42) and feed ( = 8) samples were obtained from a mink farm and cultured for the enumeration and detection of erythromycin-resistant (a macrolide; ERY)- and tetracycline-resistant (TET) enterococci. ERY and TET enterococci were detected from all fecal (mean concentrations = 6 and 7 logs, respectively) and feed (mean concentrations = 5 and 4 logs, respectively) samples. While and were detected at equal proportions among the fecal TET isolates, predominated among ERY fecal isolates. All ERY and 90% of the TET isolates ( = 50) were multidrug resistant (resistant to three or more antimicrobial classes). Among ERY isolates, while 83% of ( = 12) were positive for (B), 58% of ( = 38) isolates were positive for (C). Among ERY isolates, (M) was detected from 92% of ( = 12) and 97% of ( = 38) isolates. Conversely, however, (B) was detected in 18% of ( = 22) and 33% of ( = 27) TET isolates. Our study provides a baseline for future efforts to reduce antimicrobial resistance and improve antimicrobial stewardship in commercial mink production facilities.
物种是动物和人类的正常菌群。然而，具有抗药性的机会性病原体感染可能会危及生命。从一个水貂养殖场采集了粪便（ = 42）和饲料（ = 8）样本，用于对红霉素耐药（大环内酯类；ERY）和四环素耐药（TET）肠球菌进行计数和检测。从所有粪便（平均浓度分别为 6 和 7 对数）和饲料（平均浓度分别为 5 和 4 对数）样本中均检测到 ERY 和 TET 肠球菌。在粪便 TET 分离株中检测到 和 ，但比例相等，而在 ERY 粪便分离株中则以 为主。所有 ERY 和 90%的 TET 分离株（ = 50）均为多药耐药（对三种或更多类别的抗菌药物耐药）。在 ERY 分离株中，虽然 83%的 （ = 12）对（B）呈阳性，但 58%的 （ = 38）分离株对（C）呈阳性。在 ERY 分离株中，92%的 （ = 12）和 97%的 （ = 38）分离株检测到（M）。然而，相反，在 18%的 （ = 22）和 33%的 TET 分离株中检测到（B）。本研究为今后减少商业水貂生产设施中抗生素耐药性和改善抗生素管理的努力提供了基线数据。
