Ophthalmic Surg Lasers Imaging Retina. 2022 May;53(5):266-273. doi: 10.3928/23258160-20220415-03. Epub 2022 May 1.
To describe conjunctiva and Tenon's capsule handling during the Port Delivery System with ranibizumab (PDS) implant insertion procedure including up-front assessments, planning, and instrumentation, with emphasis placed on the peritomy, scleral dissection, and closure steps.
Surgical pearls based on experience accumulated in the PDS clinical trial program in patients with retinal diseases.
Preoperative preparation, specific instruments, and meticulous techniques are key to optimizing surgical outcomes. Before surgery, assessment of factors that affect conjunctival integrity and an in-office conjunctiva examination are conducted. Gentle, purposeful conjunctiva and Tenon's capsule handling with nontoothed forceps and suturing with a BV needle are recommended to prevent tissue damage. The peritomy is 6 mm by 6 mm, centered around the planned implant location in the superotemporal quadrant. A complete sub-Tenon's capsule dissection is achieved using a wide, robust lateral and posterior dissection technique to free tissue from the sclera and minimize tension. The globe is stabilized during scleral cutdown by grasping the sclera with fine-toothed forceps away from the incision edge to prevent tissue delamination. When closing the peritomy, both the conjunctiva and Tenon's capsule are completely captured and sutured with scleral anchoring at the apex of the peritomy to help prevent conjunctival retraction and erosion. Mitigation and detection of adverse events is critical to successful surgical outcomes.
The PDS implant insertion procedure is straightforward, but it requires planned preoperative preparation, specific instruments, and meticulous techniques. The surgical pearls described here offer insights for optimizing outcomes. .
描述在含有雷珠单抗的 Port Delivery System(PDS)植入物插入过程中对结膜和 Tenon 囊的处理,包括术前评估、计划和器械使用,重点介绍了切开术、巩膜剥离和闭合步骤。
基于在视网膜疾病患者的 PDS 临床试验计划中积累的经验总结出的手术要点。
术前准备、特定器械和精细技术是优化手术效果的关键。手术前,评估影响结膜完整性的因素并进行门诊结膜检查。建议使用无齿镊轻柔、有目的地处理结膜和 Tenon 囊,并使用 BV 针进行缝合,以防止组织损伤。切开术为 6mm 乘 6mm,以计划在上方颞象限植入物的位置为中心。采用广泛而坚固的外侧和后侧剥离技术,从巩膜上分离组织,最大限度地减少张力,以实现完整的巩膜下囊剥离。在进行巩膜切开时,通过用细齿镊夹住远离切口边缘的巩膜来稳定眼球,以防止组织分层。在闭合切开术时,完全捕获结膜和 Tenon 囊,并在切开术顶点处用巩膜锚定进行缝合,以帮助防止结膜回缩和侵蚀。减轻和检测不良事件对手术成功至关重要。
PDS 植入物插入过程简单,但需要有计划的术前准备、特定器械和精细技术。这里描述的手术要点为优化结果提供了思路。