Department of Clinical Diagnostics and Veterinary Dermatology, Faculty of Veterinary Medicine, University of Life Sciences in Lublin, ul. Gleboka 30, 20-612 Lublin, Poland.
Department of Diagnostics and Clinical Sciences, Veterinary Medicine Institute, Faculty of Biological and Veterinary Sciences, Nicolaus Copernicus University, ul. Gagarina 7, 87-100 Torun, Poland.
Pol J Vet Sci. 2022 Mar;25(1):67-73. doi: 10.24425/pjvs.2022.140842.
Cutaneous adverse food reaction (CAFR) is a common disease, affecting about 1-2% of dogs and cats. Diagnosis of the CAFR is made through elimination diet coupled with diet challenge, as methods like skin tests, patch tests, basophil degranulation tests and assessment of IgG and IgE serum levels are not sensitive enough. A partially hydrolysed salmon and pea hypoallergenic diet was evaluated in the diagnosis and treatment of CAFR in dogs and cats. The diet was used in the treatment of 13 dogs and 12 cats for 10 weeks. The Pruritus Visual Analog Scale (PVAS; dogs and cats), Canine Atopic Dermatitis Extent and Severity Index (CADESI-04; dogs) and the Scoring Feline Allergic Dermatitis (SCORFAD; cats) were used for effectiveness evaluation. In dogs, a significant decrease was reported in both CADESI-04 (from 17.3±7.5 to 10.15±7.4; p=0.028) and PVAS (from 7±1.3 to 4.76±1.8; p=0.003) after four weeks of treatment. Also in cats, both the PVAS (from 6.75±1.8 to 4±2.3; p=0.006) and SCORFAD (from 4.16±1.9 to 2.58±1.2; p=0.029) decreased significantly after four weeks. After eight weeks, a significant improvement was observed in almost all the animals. Evaluated diet was useful in the treatment of the CAFR in dogs and cats.
皮肤食物不良反应 (CAFR) 是一种常见疾病，影响约 1-2%的犬猫。CAFR 的诊断通过排除饮食和饮食挑战来进行，因为皮肤测试、斑贴试验、嗜碱性粒细胞脱颗粒试验以及 IgG 和 IgE 血清水平评估等方法不够敏感。一种部分水解三文鱼和豌豆低过敏饮食被评估用于诊断和治疗犬猫的 CAFR。该饮食用于 13 只犬和 12 只猫的治疗，为期 10 周。瘙痒视觉模拟量表 (PVAS；犬猫）、犬特应性皮炎严重程度指数 (CADESI-04；犬）和猫过敏性皮炎评分 (SCORFAD；猫）用于评估有效性。在犬中，治疗四周后 CADESI-04（从 17.3±7.5 降至 10.15±7.4；p=0.028）和 PVAS（从 7±1.3 降至 4.76±1.8；p=0.003）均显著下降。在猫中，治疗四周后 PVAS（从 6.75±1.8 降至 4±2.3；p=0.006）和 SCORFAD（从 4.16±1.9 降至 2.58±1.2；p=0.029）均显著下降。八周后，几乎所有动物的病情都有明显改善。评估饮食对犬猫 CAFR 的治疗有用。
