Veng-Pedersen P, Miller R
Int J Clin Pharmacol Ther Toxicol. 1987 Jan;25(1):10-4.
A method is presented which enables an explicit evaluation of the relative rate and extent of drug absorption of drug products using an oral drug solution as a reference, thereby avoiding the need for intravenous administration of the drug. The method is demonstrated using data from two sustained release phenylpropanolamine preparations and an oral solution of this drug in a human subject.
本文提出了一种方法，该方法能够以口服药物溶液为参比，明确评估药品的相对吸收速率和吸收程度，从而避免了对药物进行静脉给药的必要性。使用来自两种苯丙醇胺缓释制剂以及该药物在人体受试者中的口服溶液的数据对该方法进行了验证。
