Department of Population and Public Health Sciences, Keck School of Medicine, University of Southern California, Los Angeles, California, USA.
Department of Population and Public Health Sciences, Keck School of Medicine, University of Southern California, Los Angeles, California, USA
BMJ Open. 2022 May 16;12(5):e059050. doi: 10.1136/bmjopen-2021-059050.
Improved treatment regimens have led to increased survival rates among childhood cancer survivors (CCS), and more than 84% of all children diagnosed with cancer will experience long-term survival or cure. Survivors are susceptible to late effects of cancer treatment often requiring lifelong follow-up care, as many of these conditions can be prevented or mitigated with surveillance. Integrating primary care (PC) and childhood cancer survivorship care can improve follow-up for survivors, however, little integrative research exists. This scoping review aims to: identify and describe existing models of care that integrate PC and childhood cancer survivorship care, examine the effectiveness of these models of care, and characterise the barriers and facilitators for the integration of PC for CCS.
A comprehensive empirical literature search of three electronic databases (PubMed, CINAHL, and Embase) was employed to identify potentially relevant citations on 1 October 2020. The population, independent variables/intervention, comparator, outcomes, timing, setting and study design/other limiters (PICOTSS) framework was used to inform protocol development. The Preferred Reporting Items for Systematic reviews and Meta-Analyses extension for Scoping Reviews (PRISMA-ScR) checklist and explanation will be used to report study findings. The search strategy will be completed again prior to publication to ensure recent empirical research is accounted for.
This research is exempt from Institutional Review Board (IRB) review. Approval from a research ethics board for this study was not required as it does not involve human participants or unpublished secondary data. The findings from this scoping review will be disseminated through peer-reviewed scientific manuscripts, clinical conference presentations, professional networks and digital communications using social media platforms such as Twitter. This study has been registered with Open Science Framework: https://osf.io/92xbg.
儿童癌症幸存者（CCS）的治疗方案有所改进，生存率有所提高，所有被诊断患有癌症的儿童中，超过 84% 的人能够长期生存或治愈。幸存者易受癌症治疗的晚期影响，通常需要终身随访护理，因为许多此类疾病可以通过监测进行预防或缓解。将初级保健（PC）和儿童癌症生存者护理相结合可以改善幸存者的随访，但目前相关整合研究较少。本范围综述旨在：确定和描述将 PC 和儿童癌症生存者护理相结合的现有护理模式，检查这些护理模式的有效性，并描述将 PC 用于 CCS 整合的障碍和促进因素。
2020 年 10 月 1 日，我们对三个电子数据库（PubMed、CINAHL 和 Embase）进行了全面的实证文献检索，以确定可能与本研究相关的参考文献。采用人群、独立变量/干预、比较、结局、时间、地点和研究设计/其他限制（PICOTSS）框架来制定方案。将使用系统评价和荟萃分析扩展的首选报告项目（PRISMA-ScR）清单和解释来报告研究结果。在发表前，我们将再次完成搜索策略，以确保纳入最新的实证研究。
本研究豁免机构审查委员会（IRB）审查。由于本研究不涉及人类参与者或未发表的二次数据，因此不需要研究伦理委员会的批准。本范围综述的结果将通过同行评议的科学论文、临床会议演示、专业网络和数字通信（如使用 Twitter 等社交媒体平台）进行传播。本研究已在开放科学框架（Open Science Framework）上注册：https://osf.io/92xbg。
