Mayer Marcel, Nachtsheim Lisa, Arolt Christoph, Quaas Alexander, Prinz Johanna, Grosheva Maria, Klußmann Jens Peter, Wolber Philipp
Medizinische Fakultät und Uniklinik Köln, Klinik und Poliklinik für Hals-Nasen-Ohrenheilkunde, Kopf- und Hals-Chirurgie, Universität zu Köln, Kerpener Str. 62, 50937, Köln, Deutschland.
Medizinische Fakultät und Uniklinik Köln, Institut für Allgemeine Pathologie und Pathologische Anatomie, Universität zu Köln, Köln, Deutschland.
HNO. 2023 Apr;71(4):223-231. doi: 10.1007/s00106-022-01178-6. Epub 2022 May 17.
Secondary malignancies of the parotid gland frequently have a cutaneous origin and the incidence in central Europe is increasing.
The aim of this review article was to present the epidemiology, (differential) diagnostics and treatment of secondary malignancies of the parotid gland.
A literature search of the current guidelines and evidence was carried out in the web-based databank PubMed.
The incidence of secondary malignancies of the parotid gland seems to be increasing in Europe, mainly due to a rising incidence of metastases of cutaneous squamous cell carcinomas. Except for malignant lymphomas, parotidectomy is the treatment of choice in the curative situation. In the absence of clear evidence, in the case of an intact facial nerve lateral or total parotidectomy with ipsilateral neck dissection seems to be indicated, depending on the entity of the secondary malignancy.
The differential diagnostics of squamous cell carcinoma (in) of the parotid gland can be complicated. When a squamous cell carcinoma of the parotid gland is diagnosed for the first time, a dermatological full body examination and a detailed medical history should be taken with respect to skin tumors of the head and neck region. In addition to surgical treatment of the parotid gland and neck, adjuvant radiotherapy is usually indicated.
腮腺继发性恶性肿瘤常起源于皮肤,在中欧的发病率正在上升。
这篇综述文章的目的是介绍腮腺继发性恶性肿瘤的流行病学、(鉴别)诊断和治疗。
在基于网络的数据库PubMed中对当前指南和证据进行文献检索。
在欧洲,腮腺继发性恶性肿瘤的发病率似乎正在上升,主要原因是皮肤鳞状细胞癌转移的发病率上升。除恶性淋巴瘤外,腮腺切除术是根治性情况下的首选治疗方法。在缺乏明确证据的情况下,如果面神经完整,根据继发性恶性肿瘤的类型,似乎应行外侧或全腮腺切除术并同侧颈部清扫术。
腮腺鳞状细胞癌的鉴别诊断可能很复杂。首次诊断出腮腺鳞状细胞癌时,应进行皮肤科全身检查,并就头颈部皮肤肿瘤询问详细的病史。除了对腮腺和颈部进行手术治疗外,通常还需要辅助放疗。