Cooley A J, Clemmons R M, Gross T L
J Am Vet Med Assoc. 1987 Feb 15;190(4):431-2.
A 2-year-old Boston Terrier was referred because of depression and hindlimb and tail paresis. Clinical examination and serum biochemical analysis resulted in a diagnosis of encephalomyelitis and myositis. Results of testing for Dirofilaria immitis were positive. Gross and histologic examination revealed an aberrant adult heartworm infection resulting in thrombosis of the femoral artery and multiple muscular branches, with subsequent muscle necrosis and inflammation in one hindlimb. Additionally, an unusual larval-tissue interaction to microfilariae yielded a multifocal encephalomyelitis in the brain and spinal cord.
一只2岁的波士顿梗犬因精神沉郁、后肢和尾部轻瘫而被转诊。临床检查和血清生化分析诊断为脑脊髓炎和肌炎。犬恶丝虫检测结果呈阳性。大体和组织学检查显示，成虫异位感染导致股动脉及其多条肌肉分支发生血栓形成，随后一侧后肢出现肌肉坏死和炎症。此外，微丝蚴与幼虫组织的异常相互作用导致脑和脊髓出现多灶性脑脊髓炎。
