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秋田犬的假性高钾血症

Pseudohyperkalemia in Akitas.

作者信息

Degen M

出版信息

J Am Vet Med Assoc. 1987 Mar 1;190(5):541-3.

PMID:3558091
Abstract

Hyperkalemia was observed in a clinically normal Akita with normal ACTH stimulation test results, endogenous ACTH concentration, and SUN concentration. A diagnosis of pseudohyperkalemia caused by red cell hemolysis was made by comparing plasma potassium content from hemolyzed and non-hemolyzed specimens. Red cell potassium content was measured in 8 Akitas and 6 non-Akita control dogs. Six of 8 Akitas had high erythrocyte potassium content relative to their plasma and to that of the control dogs. Five of eight Akitas had microcytosis. Plasma from affected dogs had high potassium content after being refrigerated in contact with red cells for 4 hours or more. The increase in plasma potassium content was progressive with prolonged contact with the red cells and was accompanied by a decrease in plasma sodium content.

摘要

在一只临床正常、促肾上腺皮质激素(ACTH)刺激试验结果正常、内源性ACTH浓度和血清尿素氮(SUN)浓度正常的秋田犬中观察到高钾血症。通过比较溶血和未溶血标本中的血浆钾含量,诊断为由红细胞溶血引起的假性高钾血症。在8只秋田犬和6只非秋田对照犬中测量了红细胞钾含量。8只秋田犬中有6只相对于其血浆以及对照犬的血浆而言,红细胞钾含量较高。8只秋田犬中有5只存在小红细胞症。患病犬的血浆在与红细胞接触冷藏4小时或更长时间后钾含量升高。血浆钾含量的增加随着与红细胞接触时间的延长而逐渐增加,并伴有血浆钠含量的降低。

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