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样本类型及检测时间对猫血钾浓度的影响。

Effect of sample type, and timing of assay, on feline blood potassium concentration.

作者信息

Gunn-Moore Danièlle A, Reed Nicola, Simpson Kerry E, Milne Elspeth M

机构信息

Royal (Dick) School of Veterinary Studies Hospital for Small Animals, University of Edinburgh, Easter Bush Veterinary Centre, Roslin, Midlothian, Scotland EH25 9RG, UK.

出版信息

J Feline Med Surg. 2006 Jun;8(3):192-6. doi: 10.1016/j.jfms.2006.01.004.

DOI:10.1016/j.jfms.2006.01.004
PMID:16603402
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC10832853/
Abstract

Blood samples were collected from 41 cats presented for pre-anaesthetic assessments, routine geriatric screening, or re-assessment of ongoing chronic medical disorders. Samples were either left to clot or anticoagulated with lithium heparin, then assessed for their potassium concentration within 1h of collection, and again after remaining in contact with their cell pellet for 48 h. There was a significantly higher potassium concentration in the serum samples compared to the plasma samples, both in the basal and 48-h samples (although this difference was most marked in the basal samples). Ageing of both serum and plasma samples also resulted in an increase in the potassium concentration when compared with the basal values for each sample type. The mean difference (basal serum minus basal plasma) in potassium concentration was 0.47 mmol/l. While it is probable that the potassium came from either leukocytes and/or thrombocytes the mean total leukocyte count and the mean thrombocyte count were below the upper limit of the reference intervals for our laboratory and the rise in the potassium level did not appear to be directly related to either of these values.

摘要

从41只因麻醉前评估、常规老年筛查或对正在进行的慢性疾病进行重新评估而前来就诊的猫身上采集血样。血样要么让其凝固,要么用肝素锂抗凝,然后在采集后1小时内评估其钾浓度,并在与细胞沉淀接触48小时后再次评估。无论是基础样本还是48小时样本,血清样本中的钾浓度均显著高于血浆样本(尽管这种差异在基础样本中最为明显)。与每种样本类型的基础值相比,血清和血浆样本的老化也导致钾浓度升高。钾浓度的平均差异(基础血清减去基础血浆)为0.47 mmol/l。虽然钾可能来自白细胞和/或血小板,但平均总白细胞计数和平均血小板计数低于我们实验室参考区间的上限,并且钾水平的升高似乎与这些值中的任何一个均无直接关系。

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本文引用的文献

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Establishing a practical blood platelet threshold to avoid reporting spurious potassium results due to thrombocytosis.建立一个实用的血小板阈值,以避免因血小板增多症而报告假性钾结果。
Ann Clin Biochem. 2005 May;42(Pt 3):196-9. doi: 10.1258/0004563053857761.
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