Ando Takahiro, Watanabe Takatomo, Matsuo Saori, Samejima Tomoki, Yamagishi Junya, Bito Takanobu, Naruse Genki, Yoshida Akihiro, Minatoguchi Shingo, Akiyama Haruhiko, Nishigaki Kazuhiko, Minatoguchi Shinya, Okura Hiroyuki
Department of Rehabilitation, Gifu University Hospital, Japan.
Division of Clinical Laboratory and Department of Cardiology, Gifu University Hospital, Japan.
Phys Ther Res. 2022 Feb 22;25(1):18-25. doi: 10.1298/ptr.E10155. eCollection 2022.
To examine the Cardiac Rehabilitation Gifu Network (CR-GNet) feasibility in managing diseases and assisting patients in attaining physical fitness, and its impact on long-term outcomes after acute coronary syndrome (ACS).
In this prospective observational study, we enrolled 47 patients with ACS registered in the CR-GNet between February 2016 and September 2019. 37, 29, and 21 patients underwent follow-up assessments for exercise capacity (peak oxygen uptake) at 3 months, 6 months, and 1 year after discharge, respectively. Major adverse cardiac events (MACE) were compared with controls not registered in the CR-GNet.
The coronary risk factors, except blood pressure, improved at 3 and 6 months, and 1 year after discharge. These risk factors in each patient significantly reduced from 2.9 at admission to 1.6, 1.4, and 1.9 at 3 months, 6 months, and 1 year after discharge (p<0.05), respectively. Peak oxygen uptake was significantly higher at 3 months (17.5±4.9 ml/kg/min), 6 months (17.9±5.1 ml/kg/min), and 1 year (17.5±5.5 ml/kg/min) after discharge than that at discharge (14.7±3.6 ml/kg/min) (p<0.05). During follow-up, there was no significant difference; MACE did not occur in any patients in the CR-GNet but occurred in controls.
CR-GNet is a feasible option for the long-term management of ACS patients.
探讨岐阜心脏康复网络(CR-GNet)在疾病管理及协助患者实现身体健康方面的可行性,及其对急性冠状动脉综合征(ACS)后长期预后的影响。
在这项前瞻性观察性研究中,我们纳入了2016年2月至2019年9月期间在CR-GNet登记的47例ACS患者。分别有37例、29例和21例患者在出院后3个月、6个月和1年接受了运动能力(峰值摄氧量)的随访评估。将主要不良心脏事件(MACE)与未在CR-GNet登记的对照组进行比较。
除血压外,冠状动脉危险因素在出院后3个月、6个月和1年时有所改善。每位患者的这些危险因素从入院时的2.9显著降至出院后3个月、6个月和1年时的1.6、1.4和1.9(p<0.05)。出院后3个月(17.5±4.9 ml/kg/min)、6个月(17.9±5.1 ml/kg/min)和1年(17.5±5.5 ml/kg/min)时的峰值摄氧量显著高于出院时(14.7±3.6 ml/kg/min)(p<0.05)。随访期间,差异无统计学意义;CR-GNet组患者均未发生MACE,而对照组发生了MACE。
CR-GNet是ACS患者长期管理的一个可行选择。