Department of Inorganic Chemistry, Faculty of Science, Charles University, Hlavova 2030, 128 40 Prague, Czech Republic.
Dalton Trans. 2022 May 31;51(21):8085-8102. doi: 10.1039/d2dt00903j.
The discovery of ferrocene, [Fe(η-CH)], seventy years ago has significantly influenced chemical research and provided a key impetus for establishing and rapidly expanding organometallic chemistry, which has continued at a rapid pace until now. Over the years of intensive research, the ferrocene unit has been recognised as an extremely versatile platform for ligand design, materials research, and medicinal and analytical chemistry as well as many other research fields. Such wide applications of ferrocene and its derivatives are obviously rooted in the unique combination of the properties of the ferrocene moiety, which exhibits high chemical stability but is amenable to diverse synthetic modifications, has well-defined and highly specific steric properties, and displays defined and tuneable redox behaviour. The unrelenting research activity focused on ferrocene compounds and their widespread applications can be expected to continue even in the future to yield more attractive results in terms of both novelty and function.
七十年前，二茂铁（[Fe(η-CH)]）的发现极大地影响了化学研究，并为建立和快速发展有机金属化学提供了关键动力，这一领域至今仍在快速发展。在多年的深入研究中，二茂铁单元已被公认为配体设计、材料研究以及医药和分析化学以及许多其他研究领域的极其通用的平台。二茂铁及其衍生物的广泛应用显然源于二茂铁部分性质的独特组合，它表现出高度的化学稳定性，但易于进行多种合成修饰，具有明确且高度特定的空间性质，并显示出明确且可调节的氧化还原行为。对二茂铁化合物及其广泛应用的不懈研究活动预计将在未来继续进行，即使在未来，在新颖性和功能方面也将产生更具吸引力的结果。
