Department of Cardiology, Saolta Group, Galway University Hospital, Health Service Executive and National University of -Ireland Galway, Galway, Ireland.
Division of Cardiology, Department of Medicine, Verona University Hospital, Verona, Italy.
EuroIntervention. 2023 Dec 4;19(10):e807-e831. doi: 10.4244/EIJ-E-22-00018.
The Bifurcation Academic Research Consortium (Bif-ARC) project originated from the need to overcome the paucity of standardization and comparability between studies involving bifurcation coronary lesions. This document is the result of a collaborative effort between academic research organizations and the most renowned interventional cardiology societies focused on bifurcation lesions in Europe, the United States, and Asia. This consensus provides standardized definitions for bifurcation lesions; the criteria to judge the side branch relevance; the procedural, mechanistic, and clinical endpoints for every type of bifurcation study; and the follow-up methods. Considering the complexity of bifurcation lesions and their evaluation, detailed instructions and technical aspects for site and core laboratory analysis of bifurcation lesions are also reported. The recommendations included within this consensus will facilitate pooled analyses and the effective comparison of data in the future, improving the clinical relevance of trials in bifurcation lesions, and the quality of care in this subset of patients.
分叉学术研究联合会（Bif-ARC）项目源于克服涉及分叉冠状动脉病变研究之间缺乏标准化和可比性的需要。本文件是学术研究组织与专注于欧洲、美国和亚洲分叉病变的最著名介入心脏病学学会之间合作努力的结果。该共识为分叉病变提供了标准化的定义；判断边支相关性的标准；每种类型的分叉研究的程序、机制和临床终点；以及随访方法。考虑到分叉病变的复杂性及其评估，还报告了分叉病变的站点和核心实验室分析的详细说明和技术方面。本共识中的建议将有助于未来进行汇总分析和有效比较数据，提高分叉病变临床试验的临床相关性，并改善这部分患者的护理质量。
