脊髓内具有神经毡样岛的胶质神经元肿瘤：病例报告及文献复习。
Glioneuronal tumor with neuropil-like islands in the spinal cord: A case report and literature review.
机构信息
Department of Neurosurgery, Shijiazhuang Third Hospital, Shijiazhuang, China.
Department of Pathology, Second Hospital of Hebei Medical University, Shijiazhuang, China.
出版信息
Medicine (Baltimore). 2022 May 13;101(19):e29237. doi: 10.1097/MD.0000000000029237.
RATIONALE
Glioneuronal tumor with neuropil-like islands (GTNI) is a distinctive neoplasm located in the cerebrum. Moreover, spinal GTNI is extremely rare. Herein, we present a case of spinal GTNI and review the related literature.
PATIENT CONCERNS
A 38-year-old Chinese woman presented to our hospital with a 6-month history of neck pain and a 1-month history of dizziness.
DIAGNOSES
Magnetic resonance imaging revealed a large intramedullary mass spanning the length of the spinal cord from C1 to C4. Microscopic and immunohistochemical examinations of the tumor tissue revealed findings typical of GTNI.
INTERVENTIONS
The patient underwent C1 to C4 intraspinal gross tumor resection.
OUTCOMES
Follow-up results showed that the patient had no recurrence 6 months after tumor resection.
LESSONS
GTNI in the spinal cord is a highly rare neoplasm with poor prognosis. Therefore, clinicians and pathologists should differentiate GTNI from other benign glioneuronal tumors, and long-term follow-up of patients with spinal GTNI is necessary.
背景
具有神经毡样岛的胶质神经元肿瘤（GTNI）是一种位于大脑中的独特肿瘤。此外，脊髓 GTNI 极为罕见。本文报道了一例脊髓 GTNI 病例，并复习相关文献。
病例报告
一名 38 岁中国女性因颈痛 6 个月、头晕 1 个月就诊于我院。
诊断
磁共振成像显示颈 1 至颈 4 脊髓内有一长节段的髓内肿块。肿瘤组织的显微镜和免疫组化检查显示 GTNI 的典型表现。
干预
患者接受颈 1 至颈 4 椎管内肿瘤大体全切除。
结果
随访 6 个月，患者未见肿瘤复发。
结论
脊髓 GTNI 是一种罕见的高度恶性肿瘤，预后不良。因此，临床医生和病理医生应将 GTNI 与其他良性胶质神经元肿瘤区分开来，对脊髓 GTNI 患者进行长期随访是必要的。
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