INRAE, Institut Agro, UMR STLO, F-35042 Rennes, France.
Centre des Sciences du Goût et de l'Alimentation, UMR 1324 INRAE, UMR 6265 CNRS, Université de Bourgogne Franche-Comté, F-21000 Dijon, France.
J Agric Food Chem. 2022 Jun 1;70(21):6317-6327. doi: 10.1021/acs.jafc.2c01183. Epub 2022 May 18.
The present review documents the current knowledge and hypotheses on how polyphenols-saliva interactions may modulate the bioaccessibility or bioavailability of nutrients and highlights research prospects in the field. After an updated description of the different classes of dietary polyphenols and their modifications by food processing or digestion, an overview of interactions between salivary proteins and polyphenols (with an emphasis on tannins) is provided. studies show that the solubility of salivary protein-tannin complexes in gastric conditions depends on the degree of tannin polymerization, while complexes are partly solubilized by bile salts. Salivary proteins-polyphenols interactions may affect digestive processes. For example, polyphenols can bind to and inhibit salivary amylase, with downstream consequences on starch digestion. Some salivary proteins (PRPs) prevent tannin-induced reduced protein digestibility, probably through binding tannins before they interact with digestive proteases. Salivary proteins may also act as scavenger molecules to limit the intestinal uptake of tannins.
本综述文件记录了目前关于多酚-唾液相互作用如何调节营养物质的生物可及性或生物利用度的知识和假设，并强调了该领域的研究前景。在更新描述不同类别饮食多酚及其在食品加工或消化过程中的修饰后，本文概述了唾液蛋白与多酚（重点是单宁）之间的相互作用。研究表明，在胃条件下，唾液蛋白-单宁复合物的溶解度取决于单宁聚合度，而胆汁盐部分溶解复合物。唾液蛋白-多酚相互作用可能影响消化过程。例如，多酚可以与唾液淀粉酶结合并抑制其活性，从而影响淀粉消化。一些唾液蛋白（PRPs）可防止单宁引起的蛋白质消化率降低，这可能是通过在单宁与消化蛋白酶相互作用之前结合单宁来实现的。唾液蛋白也可以作为清除分子，限制单宁在肠道中的吸收。
