使用体外老年和成人消化模型评估苹果多酚的消化差异。
Evaluation of digestibility differences for apple polyphenolics using in vitro elderly and adult digestion models.
机构信息
School of Food and Biological Engineering, Hefei University of Technology, Hefei 230009, China; Chuzhou University, Chuzhou 239000, China; Collaborative Innovation Center for Food Production and Safety, School of Biological Science and Engineering, North Minzu University, Yinchuan 750000, China.
School of Food and Biological Engineering, Hefei University of Technology, Hefei 230009, China.
出版信息
Food Chem. 2022 Oct 1;390:133154. doi: 10.1016/j.foodchem.2022.133154. Epub 2022 May 5.
We evaluated the in vitro digestibility of apple polyphenols mimicking elderly and adult digestion models (dynamic and static systems). The digestibility of total apple polyphenols in small intestine was much higher in the adult dynamic system (62 μg/100 g fresh apple) compared to the static system (20 μg/100 g fresh apple) and elderly dynamic digestion conditions (33 μg/100 g fresh apple). Elderly in vitro static digestion showed better antioxidant activity than the adult system (OH and ABTS methods). Thus, the in vitro dynamic digestion system can more truly reflect the digestion of apple polyphenols than static digestion system. Moreover, elderly digestion conditions negatively influenced the digestibility of apple polyphenols including chlorogenic acid, epicatechin, phlorizin, rutin, phloretin, hyperoside, proanthocyanidin B, and quercetin. Hence, appropriate selection of in vitro digestion models for elderly is a prerequisite to exploring the digestibility of phytochemicals for the development of functional food products for elderly.
我们评估了模拟老年和成年消化模型（动态和静态系统）的苹果多酚的体外消化率。与静态系统（20μg/100g 鲜苹果）和老年动态消化条件（33μg/100g 鲜苹果）相比，成年动态系统中小肠中总苹果多酚的消化率要高得多（62μg/100g 鲜苹果）。老年体外静态消化在 OH 和 ABTS 方法上显示出比成人系统更好的抗氧化活性。因此，与静态消化系统相比，体外动态消化系统更能真实反映苹果多酚的消化情况。此外，老年消化条件会降低绿原酸、表儿茶素、根皮苷、芦丁、根皮素、圣草酚、原花青素 B 和槲皮素等苹果多酚的消化率。因此，适当选择老年体外消化模型是探索植物化学物质消化率以开发老年功能性食品产品的前提条件。
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