Shuhaiber H, Chugh T, Portoian-Shuhaiber S, Ghosh D
J Cardiovasc Surg (Torino). 1987 Mar-Apr;28(2):139-42.
During the year 1983, 170 patients underwent open heart surgery; coronary bypass surgery in 50, valve replacement in 69, valve repair in 9 and congenital heart surgery in 47. Sternal wound infection was seen in 14 patients: 10 (5.8%) patients had minor infection, recovered with extended antibiotic therapy and local hygiene, and 4 (2.3%) patients had major wound infection which required debridement and resuturing of the wound, prolonged antibiotic treatment and hospitalization. However no one developed costochondral infection. Sternal wound infection was 6 times higher among coronary bypass patients (20%) than among patients with other types of open heart surgery (3.3%). Leg wound infection was observed in 7 (14%) patients, all minor. The prevalence of diabetics was 54% among coronary-bypass patients and 6.5% among non-coronary group. Wound infection was three times higher in diabetic--or obese patients than among non diabetic--or non obese patients. Infections were not related to age, sex, smoking habits or social class. The interval between catheterisation and operation, the preoperative stay in hospital, preoperative haemoglobin or albumin level, and the time during which the patient was on the ventilator and re-opening the chest for bleeding had no influence. A significantly higher incidence of infection in patients undergoing coronary artery surgery in addition to high prevalence of diabetic or obese patients was related to the longer duration of operation procedure and the coronary perfusion time.
1983年期间,170例患者接受了心脏直视手术;其中50例行冠状动脉搭桥手术,69例行瓣膜置换术,9例行瓣膜修复术,47例行先天性心脏病手术。14例患者出现胸骨伤口感染:10例(5.8%)为轻度感染,经延长抗生素治疗和局部清洁后康复,4例(2.3%)为严重伤口感染,需要进行伤口清创和重新缝合、延长抗生素治疗及住院时间。然而,无人发生肋软骨感染。冠状动脉搭桥患者的胸骨伤口感染率(20%)比其他类型心脏直视手术患者(3.3%)高6倍。7例(14%)患者出现腿部伤口感染,均为轻度。冠状动脉搭桥患者中糖尿病患者的患病率为54%,非冠状动脉组为6.5%。糖尿病或肥胖患者的伤口感染率是非糖尿病或非肥胖患者的3倍。感染与年龄、性别、吸烟习惯或社会阶层无关。导管插入与手术之间的间隔、术前住院时间、术前血红蛋白或白蛋白水平,以及患者使用呼吸机和再次开胸止血的时间均无影响。除糖尿病或肥胖患者患病率较高外,接受冠状动脉手术患者的感染发生率显著较高与手术时间和冠状动脉灌注时间较长有关。