Department of Biomedical Informatics, The Ohio State University, Columbus, OH, 43210, USA.
Pelotonia Institute for Immuno-Oncology, The James Comprehensive Cancer Center, The Ohio State University, Columbus, OH, 43210, USA.
Nat Commun. 2022 May 18;13(1):2728. doi: 10.1038/s41467-022-30549-4.
Single-cell multi-omics (scMulti-omics) has brought transformative insights into immuno-oncology, demonstrating success in describing novel immune subsets and defining important regulators of antitumor immunity. Here, we give examples of how scMulti-omics has been used in specific tumor studies and discuss how this may develop in the future.
单细胞多组学 (scMulti-omics) 为肿瘤免疫学带来了变革性的见解,成功地描述了新型免疫亚群,并确定了抗肿瘤免疫的重要调节因子。在这里,我们举例说明了 scMulti-omics 在特定肿瘤研究中的应用,并讨论了未来的发展方向。