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因自发性膀胱破裂而诊断出的快速进展性膀胱癌

Rapidly Progressive Bladder Cancer Diagnosed because of Spontaneous Bladder Rupture.

作者信息

Hagimoto Hiroki, Sano Takeshi, Kashima Soki, Yoshino Takayuki, Goto Takayuki, Sawada Atsuro, Akamatsu Shusuke, Yamasaki Toshinari, Fujimoto Masakazu, Kajita Yoichiro, Kobayashi Takashi, Ogawa Osamu

机构信息

The Department of Urology, Kyoto University Hospital, Japan.

The Department of Diagnostic Pathology, Kyoto University Hospital, Japan.

出版信息

Case Rep Urol. 2022 May 9;2022:4586199. doi: 10.1155/2022/4586199. eCollection 2022.

Abstract

BACKGROUND

Spontaneous bladder rupture (SBR) is very rare and can be associated with advanced bladder cancer. Because of its rarity, the optimal management of bladder cancer with SBR has not been established. Herein, we report a case of SBR due to locally advanced bladder cancer, which rapidly invaded the ileum and caused peritoneal dissemination. . An 86-year-old man presented with sudden-onset lower abdominal pain and distension. The patient was diagnosed with bladder perforation and bladder tumor on contrast-enhanced computed tomography (CECT). Transurethral resection of the bladder tumor revealed an invasive urothelial carcinoma with squamous differentiation. Although radical cystectomy with lymph node dissection was planned, preoperative CECT and magnetic resonance imaging revealed enlargement of the bilateral iliac regional lymph nodes, multiple peritoneal nodules, and invasion of the bladder tumor to the ileocecum. Therefore, cystectomy and resection of ileocecum with palliative intent and bilateral cutaneous ureterostomy were performed. However, the patient's general condition rapidly worsened after surgery, and he died 74 days after the initial diagnosis.

CONCLUSIONS

We encountered a case of SBR accompanied by bladder cancer with extremely rapid progression, which suggested the importance of short-interval repeat imaging examinations. Emergency surgery should be considered when bladder cancer is suspected in patients with SBR so as not to miss the window period of a possible cure.

摘要

背景

自发性膀胱破裂(SBR)非常罕见,可能与晚期膀胱癌有关。由于其罕见性,SBR合并膀胱癌的最佳治疗方案尚未确立。在此,我们报告一例因局部晚期膀胱癌导致的SBR病例,该肿瘤迅速侵犯回肠并引起腹膜播散。一名86岁男性因突发下腹痛和腹胀就诊。在增强计算机断层扫描(CECT)上,患者被诊断为膀胱穿孔和膀胱肿瘤。经尿道膀胱肿瘤切除术显示为伴有鳞状分化的浸润性尿路上皮癌。尽管计划进行根治性膀胱切除术及淋巴结清扫,但术前CECT和磁共振成像显示双侧髂区淋巴结肿大、多个腹膜结节以及膀胱肿瘤侵犯回盲部。因此,行姑息性膀胱切除术及回盲部切除术并双侧皮肤输尿管造口术。然而,患者术后一般状况迅速恶化,在初次诊断后74天死亡。

结论

我们遇到一例SBR合并进展极快的膀胱癌病例,这提示了短间隔重复影像学检查的重要性。对于疑似SBR合并膀胱癌的患者,应考虑急诊手术,以免错过可能治愈的窗口期。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/3aac/9110233/8013cd21c924/CRIU2022-4586199.001.jpg

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