Kim Jae Heon, Yang Won Jae
Department of Urology, Soonchunhyang University College of Medicine, Hospital, 59, Daesagwan-ro, Yongsan-gu, Seoul 140-743, South Korea.
BMC Res Notes. 2014 Mar 20;7:167. doi: 10.1186/1756-0500-7-167.
Transurethral resection of bladder tumor (TURBT) may be applicable for the treatment of deeply invasive tumors in high-risk patients who are not suitable candidates for radical cystectomy. Intraperitoneal perforation is much less common, however, bladder wall perforation is still a cause for concerns because after perforation several studies have been reported to have peritoneal or abdominal metastases.
An 84-year-old female patient with multiple large enhancing masses in the urinary bladder underwent radical TURBT to remove the deeply invasive tumors because she was not a suitable candidate for a major operation. Microscopic examination of the resected specimen confirmed the muscle invasive urothelial carcinoma with partial invasion into the perivesical fat tissue. She visited again 6 months later after the operation complaining abdominal distension. Computed tomography showed perforation of urinary bladder with intraperitoneal seeding and adnexa metastasis.
Radical TURBT could be associated with delayed perforation of urinary bladder and intraperitoneal seeding.
经尿道膀胱肿瘤切除术(TURBT)可能适用于治疗那些不适合进行根治性膀胱切除术的高危患者的深部浸润性肿瘤。虽然腹膜内穿孔较为少见,但膀胱壁穿孔仍是一个令人担忧的问题,因为据报道,穿孔后有多项研究出现了腹膜或腹部转移。
一名84岁女性患者,膀胱内有多个大的强化肿块,因不适合进行大型手术而接受了根治性TURBT以切除深部浸润性肿瘤。对切除标本的显微镜检查证实为肌层浸润性尿路上皮癌,部分侵犯膀胱周围脂肪组织。术后6个月她再次就诊,主诉腹胀。计算机断层扫描显示膀胱穿孔伴腹膜种植和附件转移。
根治性TURBT可能与膀胱延迟穿孔和腹膜种植有关。