Rafiei Mehrad, Salarisedigh Somayeh, Khalili Parvin, Jamali Zahra, Sardari Farimah
Student Research Committee, Rafsanjan University of Medical Sciences, Rafsanjan, Iran.
Department of Periodontics, School of Dentistry, Rafsanjan University of Medical Sciences, Rafsanjan, Iran.
Int J Dent. 2022 May 9;2022:9990451. doi: 10.1155/2022/9990451. eCollection 2022.
While the short-term effects of hormonal events on gingival inflammation have been well described, their long-term effects on the periodontium have received less attention. Our investigation was aimed at evaluating the correlation between hormonal fluctuations and periodontal status in postmenopausal women from the profile of the Rafsanjan Cohort Study. . We used the data obtained from the profile of the Rafsanjan Cohort Study (RCS) as a part of the prospective epidemiological research studies in Iran (PERSIAN). The RCS includes 10,000 participants aged 35-70 years old. Among this population, the periodontal status data of 4143 women were available. Of these 4,143, the postmenopausal women were included in the study, and those who had a history of gingival treatment during the past 6 months were excluded from the study. Finally, 928 postmenopausal women were included in the present study. Periodontal status was assessed by measuring the clinical attachment loss, pocket depth, and bleeding on probing (BOP). Univariate and multivariate regression analyses were applied using three different models.
The results showed that 53.2% of postmenopausal women had periodontitis. There were significant differences between the participants with and without periodontitis in brushing frequency and educational status ( < 0.05). After adjusting for all potential confounders, no correlation was found between hormonal fluctuations and periodontal status.
There was no correlation between hormonal fluctuations and periodontal status.
虽然激素变化对牙龈炎症的短期影响已有详尽描述，但其对牙周组织的长期影响却较少受到关注。我们的调查旨在根据拉夫桑贾尼队列研究的概况，评估绝经后女性激素波动与牙周状况之间的相关性。我们使用了从拉夫桑贾尼队列研究（RCS）概况中获得的数据，该研究是伊朗前瞻性流行病学研究（PERSIAN）的一部分。RCS包括10000名年龄在35至70岁之间的参与者。在这一人群中，有4143名女性的牙周状况数据可用。在这4143名女性中，绝经后女性被纳入研究，而那些在过去6个月内有牙龈治疗史的女性被排除在研究之外。最终，928名绝经后女性被纳入本研究。通过测量临床附着丧失、牙周袋深度和探诊出血（BOP）来评估牙周状况。使用三种不同模型进行单变量和多变量回归分析。
结果显示，53.2%的绝经后女性患有牙周炎。在刷牙频率和教育程度方面，患有和未患有牙周炎的参与者之间存在显著差异（<0.05）。在对所有潜在混杂因素进行调整后，未发现激素波动与牙周状况之间存在相关性。
激素波动与牙周状况之间不存在相关性。
