Boukhmis Abdelkader, Nouar Mohamed El-Amin, Guerchani Mohamed Karim
Department of Cardiac Surgery, Mustapha Bacha University Hospital Center, Algiers, Algeria.
Department of Epidemiology, Mustapha Bacha University Hospital Center, Algiers, Algeria.
J Saudi Heart Assoc. 2022 Apr 2;34(1):24-31. doi: 10.37616/2212-5043.1297. eCollection 2022.
The applicability of European system for cardiac operative risk evaluation II (EuroSCORE II) and the Society of Thoracic Surgeons Predicted Risk Of Mortality (STS-PROM) as well as the initial logistic Parsonnet risk score, who have been developed from European and American datasets, is questionable outside these regions. We aimed to assess the performance of these three risk scores for patients undergoing isolated coronary artery bypass grafting (CABG) in Algeria.
Between June 2014 and June 2016, data from 235 consecutive patients, who underwent isolated CABG at a reference center in Algiers, were prospectively collected and scored according to the EuroSCORE II, STS-PROM and the Parsonnet score. Their discriminative power was evaluated by the area under the receiver operating characteristic curve (AUC) while their calibration was tested by the Hosmer-Lemeshow goodness-of-fit test.
The mean patient age was 59.08 years and 18.3% were female. The mortality at 30 days was 3.40%. The mortality expected by EuroSCORE II, STS-PROM and by Parsonnet risk score was: 1.33%, 0.78% and 3.35%, respectively. Discriminatory ability was fair for the Parsonnet risk score, good for the STS PROM and excellent for EuroSCORE II (AUCs = 0.737, 0.788, and 0.892, respectively). Regarding calibration, EuroSCORE II and STS-PROM under estimated observed mortality (Hosmer-Lemeshow test: P< 0.001 for both scores), while the Parsonnet risk score was well calibrated (Hosmer-Lemeshow test: p = 0.395).
EuroSCORE II and STS-PROM had excellent and good discriminating power, respectively, but both underestimated the risk of 30 days mortality following isolated CABG at a reference center in Algiers. The Parsonnet risk score was well calibrated but was moderately discriminating. The development of a local risk score or the recalibration of recent international risk scores is necessary.
欧洲心脏手术风险评估系统II(EuroSCORE II)、胸外科医师协会预测死亡风险(STS - PROM)以及最初的逻辑Parsonnet风险评分是根据欧美数据集开发的,在这些地区以外其适用性值得怀疑。我们旨在评估这三种风险评分对阿尔及利亚接受单纯冠状动脉旁路移植术(CABG)患者的性能。
2014年6月至2016年6月期间,前瞻性收集了阿尔及尔一家参考中心连续235例接受单纯CABG患者的数据,并根据EuroSCORE II、STS - PROM和Parsonnet评分进行评分。通过受试者工作特征曲线下面积(AUC)评估其判别能力,同时通过Hosmer - Lemeshow拟合优度检验测试其校准情况。
患者平均年龄为59.08岁,女性占18.3%。30天死亡率为3.40%。EuroSCORE II、STS - PROM和Parsonnet风险评分预期的死亡率分别为:1.33%、0.78%和3.35%。Parsonnet风险评分的判别能力一般,STS - PROM良好,EuroSCORE II优秀(AUC分别为0.737、0.788和0.892)。关于校准,EuroSCORE II和STS - PROM低估了观察到的死亡率(Hosmer - Lemeshow检验:两个评分的P均<0.001),而Parsonnet风险评分校准良好(Hosmer - Lemeshow检验:p = 0.395)。
EuroSCORE II和STS - PROM分别具有优秀和良好的判别能力,但两者都低估了阿尔及尔一家参考中心单纯CABG后30天的死亡风险。Parsonnet风险评分校准良好,但判别能力中等。有必要开发本地风险评分或重新校准近期的国际风险评分。