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拉丁美洲和加勒比地区 1979-2015 年卒中死亡率趋势。

Trends in Mortality from Stroke in Latin America and the Caribbean, 1979-2015.

机构信息

Departamento de Especialidades Médicas, Facultad de Medicina, Universidad de La Frontera, Temuco, CL.

Unidad de Neurología. Hospital Dr. Hernán Henríquez Aravena, Temuco, CL.

出版信息

Glob Heart. 2022 Apr 7;17(1):26. doi: 10.5334/gh.1114. eCollection 2022.

Abstract

BACKGROUND

Stroke is the second largest single cause of death and disability in Latin America and the Caribbean (LAC). There have been large overall declines in stroke mortality rates in most LAC countries in recent decades.

OBJECTIVE

To analyze trends in mortality caused by stroke in LAC countries in the period 1979-2015.

METHODS

We extracted data for age-standardized stroke mortality rates per 100,000 in LAC for the period 1979-2015 from the World Health Organization Mortality Database. Joinpoint regression was used to analyze the trends and compute the annual percent change (APC) in LAC as a whole and by country. Analyses were conducted by gender, region and World Bank income classification.

RESULTS

Mortality from stroke has decreased in LAC over the study period by an average APC of -1.9%. Most countries showed significant downward trends, with the sharpest decreases in Chile, Colombia and Uruguay. We recorded statistically significant decreases of -1.4% and -2.4% in mortality rates in men and women, respectively, in the whole LAC. Southern and high-income countries showed the steepest decreases.

CONCLUSIONS

Stroke mortality has decreased in LAC, in both sexes, especially in southern and high-income countries. Our results could serve as a reference for the development of primary prevention and acute management of stroke policies focused on countries with higher mortality.

摘要

背景

中风是拉丁美洲和加勒比地区(LAC)第二大致死和致残原因。近几十年来,大多数 LAC 国家的中风死亡率总体大幅下降。

目的

分析 1979 年至 2015 年期间 LAC 国家中风死亡率的趋势。

方法

我们从世界卫生组织死亡率数据库中提取了 1979 年至 2015 年 LAC 每 10 万人中风标准化死亡率的数据。使用 Joinpoint 回归分析 LAC 整体以及各国的趋势,并计算年度百分比变化(APC)。分析按性别、地区和世界银行收入分类进行。

结果

在研究期间,LAC 的中风死亡率平均每年下降 1.9%。大多数国家都呈现出明显的下降趋势,智利、哥伦比亚和乌拉圭的降幅最大。我们记录到 LAC 中男性和女性的死亡率分别下降了 1.4%和 2.4%,这具有统计学意义。南部和高收入国家的降幅最大。

结论

LAC 的中风死亡率在两性中均有所下降,特别是在南部和高收入国家。我们的结果可以为针对死亡率较高的国家制定中风一级预防和急性管理政策提供参考。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/cf20/8992764/29c1f304194f/gh-17-1-1114-g1.jpg

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