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新潟甲基汞暴露:说明成人结果的案例研究。

Methyl mercury exposure in Niigata: case studies illustrating adult outcomes.

机构信息

Research Unit of the Niigata Minamata disease, Niigata Seiryo University, Niigata, Japan.

Research Unit of the Niigata Minamata disease, Niigata Seiryo University, Niigata, Japan.

出版信息

Neurotoxicology. 2020 Dec;81:373-375. doi: 10.1016/j.neuro.2020.09.032. Epub 2020 Oct 14.

DOI:10.1016/j.neuro.2020.09.032
PMID:35587141
Abstract

Methyl mercury (MeHg) is a potent neurotoxin. Methyl mercury exposure took place at Niigata in the late 1950s and early 1960s due to industrial pollution of the Agano River. We studied adults who were exposed in utero or as children during that epidemic to determine their long-term outcomes. We contacted individuals with known exposure. Those who consented completed a questionnaire and then were interviewed. Thirty-nine subjects agreed to participate. Twenty-six subjects had health problems during their childhood and difficulties with schoolwork. As adults, some had difficulty with employment, but most led fairly normal family and social lives. Five subjects were considered to be socially maladjusted and eight others had social adjustment problems. Although some exposed subjects had health problems, many have been able to lead fairly normal lives.

摘要

甲基汞(MeHg)是一种很强的神经毒素。由于 20 世纪 50 年代末和 60 年代初阿贺野河的工业污染,新泻发生了甲基汞暴露事件。我们研究了在那次流行期间在子宫内或儿童时期暴露于甲基汞的成年人,以确定他们的长期结果。我们联系了已知接触过的人。那些同意的人完成了一份问卷,然后进行了采访。39 名受试者同意参加。26 名受试者在儿童时期有健康问题和学业困难。成年后,一些人就业困难,但大多数人过着相当正常的家庭和社会生活。有 5 名受试者被认为是社交失调,其他 8 名受试者有社交适应问题。尽管一些接触过的受试者有健康问题,但许多人能够过上相当正常的生活。

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