Department of Pharmacology, Faculty of Pharmacy, University of Khartoum, Khartoum, Sudan.
Department of Pharmacology, Faculty of Pharmacy, Al-Yarmouk College, Khartoum, Sudan.
Support Care Cancer. 2022 Oct;30(10):8519-8526. doi: 10.1007/s00520-022-07135-x. Epub 2022 May 19.
Cancer-associated thrombosis (CAT) adversely affects the quality of life and survival of people with cancer. A holistic approach is optimal for the treatment and secondary prophylaxis of venous thromboembolism (VTE) including shared decision-making around anticoagulation, considering individual risk factors for VTE recurrence, morbidities from VTE, and resources available in cancer centres around the world. Taking a global perspective on availability and cost, this paper guides the reader through the wider aspects of treatment and secondary thromboprophylaxis which, in turn, influence the recent international guidelines.
癌症相关性血栓形成(CAT)会降低癌症患者的生活质量和生存预期。在治疗和二级预防静脉血栓栓塞症(VTE)时,采用整体方法(包括围绕抗凝治疗进行共同决策)是最佳选择,需要考虑 VTE 复发的个体风险因素、VTE 导致的并发症,以及全球各地癌症中心的资源情况。本文从可及性和成本的全球视角出发,引导读者了解治疗和二级血栓预防的更广泛方面,而这些方面又反过来影响最近的国际指南。