接种 ChAdOx1 nCoV-19（Covishield）疫苗后出现单纯疱疹病毒视网膜炎：1 例报告。

Herpes simplex virus retinitis following ChAdOx1 nCoV- 19 (Covishield) vaccination for SARS CoV 2: A case report.

机构信息

Vitreo-retina and Uvea Service, Sadguru Netra Chikitsalaya, Chitrakoot, India.

Microbiology Department, Sadguru Netra Chikitsalaya, Chitrakoot, India.

出版信息

Ocul Immunol Inflamm. 2022 Jul;30(5):1282-1285. doi: 10.1080/09273948.2022.2069127. Epub 2022 May 19.

DOI:10.1080/09273948.2022.2069127

PMID:35587646

Abstract

PURPOSE

To report a case of herpes simplex virus retinitis following ChadOx1 nCoV-19 (covishield) vaccination.

CASE REPORT

A 29 year old immunocompetent male presented with unilateral disc edema with adjacent retinitis two days after receiving the first dose of ChAdOx1 nCoV-19 vaccination. Extensive investigations to rule out infective etiology were negative except for polymerase chain reaction (PCR) of the vitreous specimen which was positive for the herpes simplex virus. A diagnosis of herpes simplex (HSV) retinitis post covid vaccination was made. The patient responded well to oral antivirals and steroids.

CONCLUSION

HSV retinitis is a rare complication following the COVID-19 vaccination.

摘要

目的

报告一例接种 ChAdOx1 nCoV-19（covishield）疫苗后单纯疱疹病毒视网膜炎病例。

病例报告

一名 29 岁免疫功能正常的男性，在接种第一剂 ChAdOx1 nCoV-19 疫苗两天后出现单侧视盘水肿伴邻近视网膜病变。除玻璃体标本聚合酶链反应（PCR）检测单纯疱疹病毒阳性外，排除感染性病因的广泛检查均为阴性。诊断为新冠疫苗接种后单纯疱疹（HSV）视网膜炎。患者对口服抗病毒药物和类固醇治疗反应良好。