Suzuki Akinobu, Yamada Kentaro, Yabu Akito, Tamai Koji, Takahashi Shinji, Inui Kentaro, Okano Tadashi, Koike Tatsuya, Nakamura Hiroaki
Department of Orthopaedic Surgery, Osaka City University Graduate School of Medicine, Osaka, Japan.
Department of Orthopaedic Surgery, Osaka Saiseikai Nakatsu Hospital, Osaka, Japan.
Mod Rheumatol. 2023 Apr 13;33(3):503-508. doi: 10.1093/mr/roac049.
In rheumatoid arthritis, neck pain can be caused by inflammatory reactions or cervical lesions, but the prevalence and associated factors have not been well studied. This study aimed to investigate the prevalence of neck pain in patients with rheumatoid arthritis and elucidate the related factors.
This study included 146 patients with rheumatoid arthritis. Neck pain, quality of life, and levels of anxiety and depression were evaluated using a questionnaire. Cervical lesions and spinal alignment were evaluated using plain radiograph and magnetic resonance imaging. Factors associated with neck pain were analysed using a logistic regression model.
Fifty-six per cent of the patients had neck pain, and the quality of life scores were significantly worse in these patients. Multivariate analysis revealed age, C7 sagittal vertical axis, upper cervical lesion, and endplate erosion as factors associated with neck pain in patients with rheumatoid arthritis.
More than half the patients with rheumatoid arthritis suffer from neck pain, and neck pain affects the quality of life and activities of daily living. Neck pain was associated with upper cervical lesion and endplate erosion suggesting the importance of radiological examination in patients with rheumatoid arthritis and neck pain.
在类风湿关节炎中，颈部疼痛可能由炎症反应或颈椎病变引起，但患病率及相关因素尚未得到充分研究。本研究旨在调查类风湿关节炎患者颈部疼痛的患病率并阐明相关因素。
本研究纳入了146例类风湿关节炎患者。使用问卷评估颈部疼痛、生活质量以及焦虑和抑郁水平。使用X线平片和磁共振成像评估颈椎病变和脊柱排列。使用逻辑回归模型分析与颈部疼痛相关的因素。
56%的患者有颈部疼痛，这些患者的生活质量得分明显更差。多变量分析显示年龄、C7矢状垂直轴、上颈椎病变和终板侵蚀是类风湿关节炎患者颈部疼痛的相关因素。
超过一半的类风湿关节炎患者患有颈部疼痛，颈部疼痛会影响生活质量和日常生活活动。颈部疼痛与上颈椎病变和终板侵蚀相关，提示影像学检查在类风湿关节炎伴颈部疼痛患者中的重要性。
